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Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside
🥰Excellent
Catalog No. TN6600Cas No. 56317-05-6
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM.
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside
🥰Excellent
Purity: 98%
Catalog No. TN6600Cas No. 56317-05-6
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $112 | In Stock | |
| 5 mg | $288 | In Stock | |
| 10 mg | $525 | In Stock | |
| 25 mg | $846 | In Stock | |
| 50 mg | Inquiry | In Stock |
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Purity:98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM. |
| Targets&IC50 | α-glucosidase:5.60 ± 1.57 μM, HIV-2:5.19 μM |
| In vitro | Kaempferol 3-O-(6″- galloyl)-β-D-glucopyranoside (compounds 3; KGG) (12、25、50 μM) inhibited the expression of NLRP3 protein in RAW 264.7 cells. Treatment with the isolated compounds 3 significantly inhibited IL-1β protein expression in RAW 264.7 cells in a concentration-dependent manner.[2] Kaempferol 3-O-(6″- galloyl)-β-D-glucopyranoside (compounds 1) showed most potent inhibition at the IC50 value of 0.46 mM. The enzyme steady-state kinetic study revealed that 1 exerted competitiv inhibition with respect to ATP.[3] |
| Molecular Weight | 600.48 |
| Formula | C28H24O15 |
| Cas No. | 56317-05-6 |
| Smiles | O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC=C(O)C=C3)[C@@H]4O[C@H](COC(=O)C5=CC(O)=C(O)C(O)=C5)[C@@H](O)[C@H](O)[C@H]4O |
| Relative Density. | 1.87 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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