Name: Guanosine 5'-diphosphate ditromethamine
Brand: TargetMol
SKU: T88223
Rating: 4.5 (1 reviews)

Guanosine 5'-diphosphate ditromethamine

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Catalog No. T88223Cas No. 103192-39-8

Alias GDP ditromethamine

Guanosine 5'-diphosphate ditromethamine (GDP ditromethamine) is a nucleoside diphosphate that activates ATP-sensitive K+ channels. It acts as a potential iron mobilizer, inhibiting the interaction between hepcidin and ferroportin, and modulating the IL-6/STAT-3 pathway. This compound finds application in inflammation research, such as studying anemia of inflammation (AI).

Guanosine 5'-diphosphate ditromethamine

😃Good

Catalog No. T88223Alias GDP ditromethamineCas No. 103192-39-8

Pack Size	Price	Availability	Quantity
10 mg	Inquiry	10-14 weeks
50 mg	Inquiry	10-14 weeks

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QCan inhibitors be used for animal experiments?

AYes, our inhibitors can be used for animal/in vivo experiments. However, some compounds may not have literature supporting their use in animal experiments. In such cases, we cannot guarantee efficacy.

QHow to store the inhibitor solutions?

AAfter the stock solution is prepared, it is typically stored at -80°C and can be kept for over 1 year. It is recommended to aliquot to avoid repeated freeze-thaw cycles. For frequent use, it can be stored at 4°C for over a week.

QHow to use compounds in animal experiments? How to determine dosage and administrative routes?

AThe usage of the same compound may vary for different animal models and disease models. It is recommended to decide the usage based on the experimental purpose and refer to literatures. Common administration routes include intraperitoneal injection, oral gavage, etc. Due to the first-pass effect, compounds that can be administered orally may also be suitable for intraperitoneal injection, but those suitable for intraperitoneal injection may not necessarily be suitable for oral gavage. Dosages for different species can be converted based on tables provided on our official website. It is best to refer to specific literatures for dosages in a particular animal species. Our compounds can be used in both cell and animal experiments, but some compounds may not have literature supporting their use in animal experiments. In such cases, we cannot guarantee efficacy.

QCan PEG400 be used instead of PEG300?

APEG300 has moderate viscosity, which facilitates the dissolution and administration of drugs, while also providing good tolerability without adverse effects on animals. PEG400 can replace PEG300. PEG600 is not very recommended because its melting point is close to room temperature.

QWhat do "mg/mL" and "mM" mean?

Amg/mL" and "mM" are two different units of measurement, but represent the same maximum solubility. You can convert between them using the molar concentration calculator on our website.

Product Introduction

Bioactivity

Description	Guanosine 5'-diphosphate ditromethamine (GDP ditromethamine) is a nucleoside diphosphate that activates ATP-sensitive K+ channels. It acts as a potential iron mobilizer, inhibiting the interaction between hepcidin and ferroportin, and modulating the IL-6/STAT-3 pathway. This compound finds application in inflammation research, such as studying anemia of inflammation (AI).
Alias	GDP ditromethamine

Chemical Properties

Molecular Weight	685.47
Formula	C₁₈H₃₇N₇O₁₇P₂
Cas No.	103192-39-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.