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Elevenostat

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Elevenostat

Catalog No. T9745Cas No. 1454902-97-6

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.

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Pack Size	Price	Availability
5 mg	$39	In Stock
10 mg	$64	In Stock
25 mg	$122	In Stock
50 mg	$197	In Stock
100 mg	$367	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock

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Product Introduction

Bioactivity

Description	Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.
In vitro	Elevenostat induced cell death in MM cell lines[1].
In vivo	Elevenostat produced similar anti-MM activity in vivo, improving survival among mice inoculated with 5TGM1 MM cells[1].

Chemical Properties

Molecular Weight	315.32
Formula	C16H17N3O4
Cas No.	1454902-97-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 250 mg/mL (792.85 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1714 mL	15.8569 mL	31.7138 mL	158.5691 mL
5 mM	0.6343 mL	3.1714 mL	6.3428 mL	31.7138 mL
10 mM	0.3171 mL	1.5857 mL	3.1714 mL	15.8569 mL
20 mM	0.1586 mL	0.7928 mL	1.5857 mL	7.9285 mL
50 mM	0.0634 mL	0.3171 mL	0.6343 mL	3.1714 mL
100 mM	0.0317 mL	0.1586 mL	0.3171 mL	1.5857 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc