Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside, an orally active phenolic compound derived from the Geranium species, demonstrates anti-inflammatory properties and holds potential for treating edema and aortic endothelium-dependent relaxation injury [1].

Quercetin-3-O-(2''-O-galloyl)-β-D-glucopyranoside, when administered orally at a single dose of 100 mg/kg to male Swiss albino mice, attenuated PGE2-induced paw edema, carrageenan-induced hind paw swelling, and p-benzoquinone-induced writhing response [1]. Additionally, a single topical application of 0.5 mg/ear of this compound suppressed 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear edema in the same model [1].