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2-Methylthioadenosine diphosphate trisodium
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Catalog No. T23581Cas No. 475193-31-8
Alias 2-Methylthio-ADP trisodium, 2-MeS-ADP trisodium, 2MeSADP trisodium, 2 Methylthio ADP trisodium, 2 MeS ADP trisodium
2-Methylthioadenosine diphosphate trisodium (2-MeS-ADP) is the salt form of 2-Methylthioadenosine diphosphate, a synthetic analog of adenosine diphosphate (ADP), a potent purinergic P2Y receptor agonist that agonizes human P2Y13 at nanomolar levels, mouse P2Y13 and human P2Y12, induces platelet aggregation and morphological changes, and is indicated for neurological and cardiovascular disease studies.
2-Methylthioadenosine diphosphate trisodium
😃Good
Catalog No. T23581Alias 2-Methylthio-ADP trisodium, 2-MeS-ADP trisodium, 2MeSADP trisodium, 2 Methylthio ADP trisodium, 2 MeS ADP trisodiumCas No. 475193-31-8
2-Methylthioadenosine diphosphate trisodium (2-MeS-ADP) is the salt form of 2-Methylthioadenosine diphosphate, a synthetic analog of adenosine diphosphate (ADP), a potent purinergic P2Y receptor agonist that agonizes human P2Y13 at nanomolar levels, mouse P2Y13 and human P2Y12, induces platelet aggregation and morphological changes, and is indicated for neurological and cardiovascular disease studies.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $198 | 35 days | |
| 5 mg | $917 | 35 days | |
| 10 mg | $1,380 | 35 days |
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Concentration:5.39 mg/mL
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Product Introduction
Bioactivity
Chemical Properties
| Description | 2-Methylthioadenosine diphosphate trisodium (2-MeS-ADP) is the salt form of 2-Methylthioadenosine diphosphate, a synthetic analog of adenosine diphosphate (ADP), a potent purinergic P2Y receptor agonist that agonizes human P2Y13 at nanomolar levels, mouse P2Y13 and human P2Y12, induces platelet aggregation and morphological changes, and is indicated for neurological and cardiovascular disease studies. |
| In vitro | 2-Methylthioadenosine diphosphate trisodium is a potent inhibitor of cyclic AMP accumulation in intact platelets exposed to PGE1 and is a potent human platelet aggregator.[1] |
| Alias | 2-Methylthio-ADP trisodium, 2-MeS-ADP trisodium, 2MeSADP trisodium, 2 Methylthio ADP trisodium, 2 MeS ADP trisodium |
| Molecular Weight | 539.24 |
| Formula | C11H14N5Na3O10P2S |
| Cas No. | 475193-31-8 |
| Smiles | O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP([O-])([O-])=O)([O-])=O)N2C3=NC(SC)=NC(N)=C3N=C2.[Na+].[Na+].[Na+] |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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