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Prasugrel Hydrochloride

Catalog No. T6952Cas No. 389574-19-0
Alias Prasugrel HCl, PCR 4099 (hydrochloride), LY 640315 Hydrochloride, LY 640315, Effient Hydrochloride

Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.

Prasugrel Hydrochloride

Prasugrel Hydrochloride

Purity: 99.79%
Catalog No. T6952Alias Prasugrel HCl, PCR 4099 (hydrochloride), LY 640315 Hydrochloride, LY 640315, Effient HydrochlorideCas No. 389574-19-0
Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$55In Stock
25 mg$90In Stock
50 mg$133In Stock
100 mg$197In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:99.79%
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Product Introduction

Bioactivity
Description
Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.
Targets&IC50
Platelet:1.8 μM.
In vivo
Prasugrel significantly inhibits arterio-venous (AV) shunt and electrically induced arterial thrombosis in single dose ranges of 0.3 to 3 mg/kg and of 0.3 and 1 mg/kg/day for multiple doses. These doses are similar to doses with inhibition of platelet activation via P2Y12 receptors, suggesting that the protective effects of prasugrel in these cerebral infarction and peripheral arterial occlusive disease models reflect P2Y12 inhibitions on platelets by prasugrel's active metabolite. Prasugrel also significantly prevents progression of peripheral vascular lesions[1].
AliasPrasugrel HCl, PCR 4099 (hydrochloride), LY 640315 Hydrochloride, LY 640315, Effient Hydrochloride
Chemical Properties
Molecular Weight409.9
FormulaC20H20FNO3S·HCl
Cas No.389574-19-0
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 43 mg/mL (104.9 mM)
Ethanol: 9 mg/mL (21.95 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.4396 mL12.1981 mL24.3962 mL121.9810 mL
5 mM0.4879 mL2.4396 mL4.8792 mL24.3962 mL
10 mM0.2440 mL1.2198 mL2.4396 mL12.1981 mL
20 mM0.1220 mL0.6099 mL1.2198 mL6.0990 mL
DMSO
1mg5mg10mg50mg
50 mM0.0488 mL0.2440 mL0.4879 mL2.4396 mL
100 mM0.0244 mL0.1220 mL0.2440 mL1.2198 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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