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Search Results for " antiplatelet "

Targets

Compounds

Natural Products

Cat No.	Product Name	Synonyms	Targets
T12316	Oral antiplatelet agent 1		Others
	Oral antiplatelet agent 1 is a potent antiplatelet agent with an IC50 of 2.94 μM in vitro.		Others
T63335	Antiplatelet agent 2
	Antiplatelet agent 2 is a ticagrelor analogue that exhibits anti-platelet effects and can be used in platelet agglutination studies.
T63334	Antiplatelet agent 1
	Antiplatelet agent 1 is a ticagrelor analogue that exhibits anti-platelet effects and can be used in platelet agglutination studies.
T9153	Picotamide		Others
	Picotamide has anticoagulant and fibrinolytic properties.		Others
T5036	Cangrelor tetrasodium		GPR , P2Y Receptor
	Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.		GPR , P2Y Receptor
T3536	AZD1283		P2Y Receptor
	AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithromboti...		P2Y Receptor
T11339	Furegrelate sodium	U-63557A	PPAR
	Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synthase in human platelet microsomes with an IC50 of 15 nM.		PPAR
T21712	BAY 41-8543		Others , Guanylate cyclase
	BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).		Others , Guanylate cyclase
T6236	Ozagrel	OKY-046,Domenan	Thrombin , Prostaglandin Receptor
	Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch...		Thrombin , Prostaglandin Receptor
T1618	Dipyridamole	Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine	PDE
	Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.		PDE
T6814	Cyproheptadine hydrochloride	Periactin hydrochloride,Anarexol,Cyproheptadine HCl,Nuran	5-HT Receptor
	Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.		5-HT Receptor
T6625	Ozagrel hydrochloride	Ozagrel HCl,OKY-046 HCl	Thrombin , Prostaglandin Receptor
	Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.		Thrombin , Prostaglandin Receptor
T0230	Prasugrel	LY640315,CS-747,PCR 4099	P2Y Receptor
	Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those...		P2Y Receptor
T9138	Indirubin-3′-oxime	Indirubin-3'-monoxime	GSK-3 , CDK , JNK
	Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.		GSK-3 , CDK , JNK
T0182L	Clopidogrel hydrogen sulfate	(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel	P450 , P2Y Receptor
	Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.		P450 , P2Y Receptor
T6952	Prasugrel Hydrochloride	LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl	P2Y Receptor
	Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.		P2Y Receptor
T4190	Ticlopidine	PCR 5332,Ticlid	ATPase , Adiponectin receptor
	Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.		ATPase , Adiponectin receptor
T11177	Elinogrel	PRT060128	P2Y Receptor
	Elinogrel (PRT060128) is a competitive and reversible antagonist of platelet P2Y12 with IC50 of 20 nM and exhibits potent antiplatelet effects.		P2Y Receptor
T24733	Roxifiban acetate	MK 0853,DMP754,DMP 755,DMP 754 acetate,DMP 754,DMP-754 acetate,DMP754 acetate,DMP-754	Integrin
	Roxifiban acetate（DMP 754 acetate） is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used in the study of human thrombocytopenia.		Integrin
T11825	LCB-2853		PPAR
	LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.		PPAR
T27335	Floctafenine	RU 15750,R-4318,R 4318,RU-15750,R4318	COX
	Floctafenine (R-4318) is an orally available nonsteroidal anti-inflammatory compound that is a COX-I and COX-2 inhibitor and interferes with the antiplatelet effects of aspirin.Floctafenine has analgesic activity and is ...		COX
T12596	(4E)-SUN9221		5-HT Receptor , Adrenergic Receptor
	(4E)-SUN9221 is a potent dual α1-adrenergic receptor and 5-HT2 receptor antagonist that shows antihypertensive and antiplatelet aggregation activity in hypertensive rats.		5-HT Receptor , Adrenergic Receptor
T5146	Eptifibatide acetate (148031-34-9 free base)	Eptifibatide acetate	Others
	Eptifibatide acetate (148031-34-9 free base) (Eptifibatide acetate) , an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl res...		Others
T0182L2	(±) Clopidogrel hydrogen sulfate	Plavix,Clopidogrel hydrogen sulfate,Iscover	P2Y Receptor
	(±) Clopidogrel hydrogen sulfate (Iscover) , an antiplatelet agent pharmacologically and structurally analogous to ticlopidine, is used to inhibit blood clots in various conditions such as cerebrovascular disease, periph...		P2Y Receptor
T1066	Ketanserin	R41468,Ketanserin tartrate,Ketanserinum	Potassium Channel , 5-HT Receptor , Autophagy
	Ketanserin (Ketanserinum) is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihypertensive and antiplatelet activities. Following administration,...		Potassium Channel , 5-HT Receptor , Autophagy
T17039	Terbogrel	BIBV 308SE	Prostaglandin Receptor
	Terbogrel is an oral thromboxane A2 receptor antagonist (IC50 is about 10 nM) and thromboxane A2 synthase inhibitor (IC50 is about 10 nM). Terbogrel is an antiplatelet compound that inhibits platelet aggregation and is a...		Prostaglandin Receptor
T16328	Nitroaspirin	NCX 4016	Apoptosis , COX
	Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin induces significant induction of cell cycle arrest and apoptosis...		Apoptosis , COX
T28427	Plafibride
	Plafibride is an antiplatelet and antilipidemic agent.
T10083	Desethyl KBT-3022		Others
	Desethyl KBT-3022 is an active metabolite of the antiplatelet compound KBT-3022.		Others
T24760	Satigrel	E 5510,E5510
	Satigrel is a new antiplatelet agent. It also inhibits platelet accumulation in prosthetic arterial grafts.
T26052	RE 1492	RE1492,RE-1492
	RE 1492 is an oligoamine that gives it an antiplatelet effect when combined with antithrombic drugs.
T7380	Protease-Activated Receptor-4		Protease-activated Receptor
	Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy		Protease-activated Receptor
T26071	Rhamnetin tetraacetate
	Rhamnetin tetraacetate is a potent antiplatelet compound that strongly inhibits platelet aggregation induced by arachidonic acid, collagen and PAF.
T61811	GPVI antagonist 3
	GPVI antagonist 3 (Compound 2) is a potential antagonist that shows promising antiplatelet activity by selectively inhibiting the interaction between the Glycoprotein VI (GPVI) receptor and its ligands. It demonstrates p...
T14684	BMS-986120		Others
	BMS-986120 is a first-in-class oral and reversible protease-activated receptor 4 (PAR4) antagonist. With IC50s of 9.5 nM and 2.1 nM in human and monkey blood, respectively. BMS-986120 has potent and selective antiplatele...		Others
T36759	SAR 216471 hydrochloride
	Potent P2Y12 antagonist (IC50 = 17 nM). Displays antiplatelet and antithrombotic activity in vivo. Orally available. Boldron et al (2014) N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylp...
T17200	UDM-001651		Others
	UDM-001651 is an effective and orally bioavailable protease-activated receptor 4 antagonists (IC50=4 nM; Kd=1.4 nM). UDM-001651 displays antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggr...		Others
T24732	Roxifiban	DMP-754,DMP754,DMP 754
	Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.
T36726	6-keto Prostaglandin E1	6-keto Prostaglandin E1
	6-keto Prostaglandin E1 is a bioactive derivative of PGE1 that plays a role in antiplatelet aggregation and depolymerization.
T28044	MIPS-9922
	MIPS-9922 is a potent and selective PI3Kβ inhibitor with antiplatelet activity. MIPS-9922 inhibited integrin αIIbβ3 activation and αIIbβ3 dependent platelet adhesion to immobilized vWF under high shear. MIPS-9922 also p...
T5501	Clopidogrel thiolactone	2-oxoclopidogrel	P2Y Receptor
	Clopidogrel thiolactone (2-oxoclopidogrel) is a potent P2Y12 receptor inhibitor and a potent antiplatelet aggregation compound.Clopidogrel thiolactone is the active metabolic intermediate resulting from the first oxidati...		P2Y Receptor
T76979	Tadocizumab
	Tadocizumab (C4G1; YM-337), a humanized monoclonal antibody targeting integrin αIIbβ3, exhibits antiplatelet and antithrombotic properties. It is utilized in research into cardiovascular diseases [1] [2].
T5020	Eptifibatide	Eptifibatide Acetate,Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2	Others
	Eptifibatide (Eptifibatide Acetate), an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue.		Others
T82898	Bentracimab	PB 2452,MEDI 2452
	Bentracimab (PB 2452) is a monoclonal antibody that effectively neutralizes Ticagrelor and its primary active metabolite by binding with high affinity, facilitating the rapid reversal of Ticagrelor's antiplatelet effects...
T70335	Cangrelor free acid
	Cangrelor is a P2Y12 inhibitor, and was approved in June 2015 as an antiplatelet drug for intravenous application. Cangrelor is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhi...
T60576	Cyproheptadine
	Cyproheptadine is a potent and orally active antagonist of the 5-HT 2A receptor. Cyproheptadine has antidepressant and antiserotonergic effects. Cyproheptadine also has antiplatelet and thromboprotective activities that ...
T17231	Vicagrel		Others
	Vicagrel is an effective, orally active antiplatelet compound that enhances the inhibitory effect of aspirin on platelet aggregation and thrombosis in rodents by irreversibly inhibiting P2Y12 receptors and reducing metab...		Others
T37176	Edoxaban impurity 6
	Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaba...

Compounds

Oral antiplatelet agent 1

T12316

Synonym:

Target: Others

Antiplatelet agent 2

T63335

Synonym:

Target:

Antiplatelet agent 1

cangrelor tetrasodium

T5036

Synonym:

Target: GPR, P2Y Receptor

Target: Others, Guanylate cyclase

Ozagrel

T6236

Synonym: OKY-046,Domenan

Target: Thrombin, Prostaglandin Receptor

Dipyridamole

T1618

Synonym: Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine

Target: PDE

Cyproheptadine hydrochloride

T6814

Synonym: Periactin hydrochloride,Anarexol,Cyproheptadine HCl,Nuran

Target: 5-HT Receptor

Ozagrel hydrochloride

T6625

Synonym: Ozagrel HCl,OKY-046 HCl

Target: Thrombin, Prostaglandin Receptor

Prasugrel

T0230

Synonym: LY640315,CS-747,PCR 4099

Target: P2Y Receptor

Indirubin-3′-oxime

T9138

Synonym: Indirubin-3'-monoxime

Target: GSK-3, CDK, JNK

Clopidogrel hydrogen sulfate

T0182L

Synonym: (S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel

Target: P450, P2Y Receptor

Prasugrel Hydrochloride

T6952

Synonym: LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl

Target: P2Y Receptor

Ticlopidine

T4190

Synonym: PCR 5332,Ticlid

Target: ATPase, Adiponectin receptor

Synonym: MK 0853,DMP754,DMP 755,DMP 754 acetate,DMP 754,DMP-754 acetate,DMP754 acetate,DMP-754

Synonym: RU 15750,R-4318,R 4318,RU-15750,R4318

Target: 5-HT Receptor, Adrenergic Receptor

Eptifibatide acetate (148031-34-9 free base)

T5146

Synonym: Eptifibatide acetate

Target: Others

(±) Clopidogrel hydrogen sulfate

T0182L2

Synonym: Plavix,Clopidogrel hydrogen sulfate,Iscover

Target: P2Y Receptor

Ketanserin

T1066

Synonym: R41468,Ketanserin tartrate,Ketanserinum

Target: Potassium Channel, 5-HT Receptor, Autophagy

Terbogrel

T17039

Synonym: BIBV 308SE

Target: Prostaglandin Receptor

Nitroaspirin

T16328

Synonym: NCX 4016

Target: Apoptosis, COX

Synonym: E 5510,E5510

Target:

RE 1492

T26052

Synonym: RE1492,RE-1492

Target:

Protease-Activated Receptor-4

T7380

Synonym:

Target: Protease-activated Receptor

Rhamnetin tetraacetate

SAR 216471 hydrochloride

Synonym: DMP-754,DMP754,DMP 754

Target:

6-keto Prostaglandin E1

T36726

Synonym: 6-keto Prostaglandin E1

Clopidogrel thiolactone

T5501

Synonym: 2-oxoclopidogrel

Synonym: Eptifibatide Acetate,Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2

Target: Others

Bentracimab

T82898

Synonym: PB 2452,MEDI 2452

Cat No.	Product Name	Synonyms	Targets
T5814	Aurantiamide	TMC-58B	p38 MAPK , NF-κB
	Aurantiamide has anti-cancer, anti-inflammatory and antinociceptive activities, it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimula...		p38 MAPK , NF-κB
T2S2109	Skimmianine	beta-Fagarine,Skimmianin,Chloroxylonine,Skimmiamine	Others
	1. Skimmianine (Chloroxylonine) is a spasmolytic agent. 2. Skimmianine (Chloroxylonine) shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.		Others
T2230	Paeoniflorin	Peoniflorin	HSP , COX
	Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.		HSP , COX
T8121	Octacosanoic acid		Anti-infection
	Octacosanoic acid has antiplatelet and antithrombotic effects.		Anti-infection
T2953	Ligustrazine hydrochloride	Tetramethylpyrazine hydrochloride,Tetramethylpyrazine HCl,Chuanxiongzine hydrochloride,Tetrapyrazine HCl	Others
	Ligustrazine hydrochloride (Chuanxiongzine hydrochloride) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.		Others
TN1626	Eugenin		Others
	Eugenin is a chromone isolated from Peucedanum japonicum.Eugenin potent antiplatelet aggregation activity		Others
TN2086	Piperlotine A		Antibacterial
	Piperlotine A is an alkaloid that can be extracted from Piperonyssinus rolfsii and has antiplatelet aggregation activity.Piperlotine A showed inhibition of Mycobacterium tuberculosis in an in vitro assay with a MIC value...		Antibacterial
TN2027	Oxysanguinarine	8-Oxosanguinarine,Hydroxysanguinarine	Parasite
	Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus.		Parasite
TN3831	(-)-Denudatin B	Denudatin B	ATPase , Potassium Channel , Calcium Channel , PAFR
	(-)-Denudatin B (Denudatin B) is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoinositides breakdown induced by collagen and thrombin.		ATPase , Potassium Channel , Calcium Channel , PAFR
T8061	Citronellal	(±)-Citronellal	Others
	Citronellal ((±)-Citronellal) is a monoterpene predominantly formed by the secondary metabolism of plants, producing antithrombotic, antiplatelet, and antihypertensive activities.		Others
T2722	Ligustrazine	Tetramethylpyrazine	Apoptosis , Antioxidant
	Ligustrazine (Tetramethylpyrazine), a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) shows anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.		Apoptosis , Antioxidant
T3915	Ginsenoside Ro	Chikusetsusaponin 5,Polysciasaponin P3,Chikusetsusaponin V	Calcium Channel , Reductase , Prostaglandin Receptor
	Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist with an IC50 of 155 μM.		Calcium Channel , Reductase , Prostaglandin Receptor
T5725	Salvianolic acid B	lithospermic acid B,Dan Shen Suan B	Sirtuin , Autophagy
	Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia extract. It plays significant role of antioxidant effect; antiplatelet aggregation, anticoagulant, and antithrombotic effect		Sirtuin , Autophagy
T2727	Salvianolic acid B		Others
	Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia extract. It plays significant role of antioxidant effect; antiplatelet aggregation, anticoagulant, and antithrombotic effect		Others
T77563	4-Ethylcatechol		DNA
	4-Ethylcatechol is present in red wine and can be extracted from Glechoma longituba (NaKai) Kupr.4-Ethylcatechol induces DNA damage in the presence of Cu(II).4-Ethylcatechol is a potent antiplatelet compound.		DNA
T3S0195	Nootkatone		AMPK
	1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent obesity and improve physical performance through AMPK activa...		AMPK
TN6097	Girinimbine	Girinimbin	Apoptosis , Antioxidant , Antibacterial
	Girinimbine (Girinimbin) is a carbazole alkaloid isolated from the plants M. koenigii, M. koenigii and Murraya koenigii.Girinimbine has a wide range of biological effects, including apoptosis, antitrypanosomal, antiplate...		Apoptosis , Antioxidant , Antibacterial
T6S1784	Brazilin	Natural Red 24,Braziletto,Brasilin,Superbresiline	Apoptosis , Others , AMPK , Autophagy
	1. Brazilin (Braziletto) exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated and tumor cell specific sign...		Apoptosis , Others , AMPK , Autophagy
TN1254	3'-Methoxydaidzein		Sodium Channel
	3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 nM, respectively. 3'-Methoxydaidzein was specific for colla...		Sodium Channel
T5S2358	Dehydrocorydaline	Dehydrocorydalin,13-Methylpalmatine	BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...		BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
TN4796	Piperlotine D		PAFR
	Piperlotine D shows potent antiplatelet aggregation activity.		PAFR
T10637	Butin		Others
	Butin, a major biologically active flavonoid isolated from the Dalbergia odorifera, has strong antioxidant, anti-inflammatory and antiplatelet activities.		Others
TN2087	Piperlotine C		PAFR
	Piperlotine C shows potent antiplatelet aggregation activity.		PAFR
T40595	Rubiayannone A
	Rubiayannone A is an anthraquinone glycoside with an antiplatelet aggregation activity.
TN4373	Kaempferol tetraacetate		Antifection
	Kaempferol tetraacetate is a potent antiplatelet agent. It exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1.		Antifection
TN1954	Moscatin		Others
	Moscatin exhibits antiplatelet aggregation activity.		Others
TN4922	Rubiarbonol B		Others
	Rubiarbonol B may have antiplatelet aggregation activities.		Others
TN1044	Quercetin 3-O-neohesperidoside		Others
	Quercetin 3-O-neohesperidoside shows anti-atherosclerosis, and antiplatelet aggregation activities.		Others
TMA1944	Protopine hydrochloride		EGFR , cAMP
	Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracellular calcium concentration.Protopine seems to inhibit the h...		EGFR , cAMP
TN2040	Panaxynol		BCL , Caspase , HIF
	Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation.		BCL , Caspase , HIF
TMA0593	Broussoflavonol F		Tyrosinase
	Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggregation. Broussoflavonol F shows inhibitory activities on mush...		Tyrosinase
T79948	Kadsurenin B
	Kadsurenin B, a platelet-activating factor (PAF) antagonist, exhibits neuroprotective properties and has a broad spectrum of pharmacological research applications, including antibacterial, anti-inflammatory, neuroprotect...
TN1953	Morusinol		ERK , MEK , Autophagy , Ras
	Morusinol is a flavonoid extracted from the root bark of Morus alba. Morusinol has antiplatelet and anticancer activities, inhibits arterial thrombosis in vivo, and exerts antitumor activity by inducing autophagy, G2/M c...		ERK , MEK , Autophagy , Ras
TN5901	Cudratricusxanthone A
	Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to in...
T35624	Ajoene
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =...