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Oxysanguinarine

Oxysanguinarine
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Purity:99.57%
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Oxysanguinarine

Catalog No. TN2027Cas No. 548-30-1
Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus.
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Pack SizePriceAvailabilityQuantity
1 mg$55In Stock
5 mg$147In Stock
10 mg$239In Stock
25 mg$395In Stock
50 mg$589In Stock
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Product Introduction

Bioactivity
Description
Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus.
In vitro
A total of 2750 phytochemicals from different medicinal plants were selected for this study. These plants grow naturally in the climate of Pakistan and India and have been used for the treatment of various pathologies in humans for a long-time. The ADMET studies, molecular docking and density functional theory (DFT) based analysis was carried out to determine the potential inhibitory properties of these phytochemicals. The ADMET analysis and docking results revealed nine phytochemicals, i.e. Silymarin, Flavobion, Derrisin, Isosilybin, Mundulinol, Silydianin, Isopomiferin, Narlumicine and Oxysanguinarine to have potential inhibitory properties against DENV and can be considered for additional in vitro and in vivo studies to assess their inhibitory effects against DENV replication. They exhibited binding affinity ≥ -8 kcal/mol against DENV4-NS4B. Furthermore, DFT-based analysis revealed high reactivity for these nine phytochemicals in the binding pocket of DENV4-NS4B, based on ELUMO, EHOMO and band energy gap. INTERPRETATION &[1]
Alias8-Oxosanguinarine, Hydroxysanguinarine
Chemical Properties
Molecular Weight347.32
FormulaC20H13NO5
Cas No.548-30-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: Insoluble

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