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Panaxynol
Catalog No. TN2040Cas No. 81203-57-8
Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation.
Panaxynol
Catalog No. TN2040Cas No. 81203-57-8
Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $710 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $730 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation. |
| In vitro | Panaxynol (0.1 mg/ml) inhibited markedly the aggregation of washed platelets induced by collagen, arachidonic acid, ADP, ionophore A23187, PAF and thrombin while ginsenosides had no significant effect on the aggregation but ginsenoside Ro (1 mg/ml) inhibited the ATP release of platelets. Less inhibitory effect of Panaxynol was observed in the aggregation of platelet-rich plasma. Thromboxane B2 formation of platelets was inhibited by Panaxynol but not by ginsenosides. The antiplatelet effect of Panaxynol was dependent on the incubation time and the aggregability of platelets inhibited by Panaxynol could not easily be recovered after washing the platelets. In human platelet-rich plasma, Panaxynol prevented secondary aggregation and completely blocked ATP release from platelets induced by epinephrine and ADP. Both Panaxynol and ginsenoside Rg2 inhibited the rise of intracellular calcium caused by collagen[1] |
| Molecular Weight | 244.37 |
| Formula | C17H24O |
| Cas No. | 81203-57-8 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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