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Acriflavine Hydrochloride

Catalog No. T19832Cas No. 8063-24-9
Alias Acriflavine HCl

Acriflavine Hydrochloride (Acriflavine HCl) is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.

Acriflavine Hydrochloride

Acriflavine Hydrochloride

Purity: 99.69%
Catalog No. T19832Alias Acriflavine HClCas No. 8063-24-9
Acriflavine Hydrochloride (Acriflavine HCl) is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
Pack SizePriceAvailabilityQuantity
500 mg$41In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Purity:99.69%
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Product Introduction

Bioactivity
Description
Acriflavine Hydrochloride (Acriflavine HCl) is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
AliasAcriflavine HCl
Chemical Properties
Molecular Weight259.73
FormulaC14H14ClN3
Cas No.8063-24-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/ml (115.5 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8502 mL19.2508 mL38.5015 mL192.5076 mL
5 mM0.7700 mL3.8502 mL7.7003 mL38.5015 mL
10 mM0.3850 mL1.9251 mL3.8502 mL19.2508 mL
20 mM0.1925 mL0.9625 mL1.9251 mL9.6254 mL
50 mM0.0770 mL0.3850 mL0.7700 mL3.8502 mL
100 mM0.0385 mL0.1925 mL0.3850 mL1.9251 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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