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Spinosin

🥰Excellent
Catalog No. T6S2227Cas No. 72063-39-9
Alias Flavoayamenin

1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas.

Spinosin

Spinosin

🥰Excellent
Purity: 98.68%
Catalog No. T6S2227Alias FlavoayameninCas No. 72063-39-9
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas.
Pack SizePriceAvailabilityQuantity
20 mg$90In Stock
1 mL x 10 mM (in DMSO)$70In Stock
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Purity:98.68%
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COA HNMR HPLC
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Product Introduction

Bioactivity
Description
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas.
AliasFlavoayamenin
Chemical Properties
Molecular Weight608.54
FormulaC28H32O15
Cas No.72063-39-9
Smiles[H][C@@]1(O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2c2c(OC)cc3oc(cc(=O)c3c2O)-c2ccc(O)cc2)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.1.72 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: Soluble
DMSO: 91 mg/mL (149.5 mM)
Pyridine, Methanol, etc.: Soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6433 mL8.2164 mL16.4328 mL82.1639 mL
5 mM0.3287 mL1.6433 mL3.2866 mL16.4328 mL
10 mM0.1643 mL0.8216 mL1.6433 mL8.2164 mL
20 mM0.0822 mL0.4108 mL0.8216 mL4.1082 mL
50 mM0.0329 mL0.1643 mL0.3287 mL1.6433 mL
100 mM0.0164 mL0.0822 mL0.1643 mL0.8216 mL

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Keywords

InhibitorneuroprotectiveinhibitAβ1-42Spinosin
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