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(S)-Laudanosine

Name: (S)-Laudanosine
Brand: TargetMol
SKU: TN7543
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN7543Cas No. 2688-77-9

Alias L-Laudanosine, L-(+)-Laudanosine, (+)-Laudanosine

(S)-Laudanosine is the corresponding isomer of Laudanosine, which crosses the blood-brain barrier, causing euphoria and seizures, with potential systemic toxicity and analgesic effects. In the cardiovascular system, high plasma concentrations can lead to hypotension and bradycardia.Laudanosine interacts with γ-aminobutyric acid, opioid, and nicotinic acetylcholine receptors, and inhibits the low-affinity GABA receptor, as well as competitively binds to the opioid receptor Mu-1 receptor.

(S)-Laudanosine

🥰Excellent

Catalog No. TN7543Alias L-Laudanosine, L-(+)-Laudanosine, (+)-LaudanosineCas No. 2688-77-9

Pack Size	Price	Availability
1 mg	$195	In Stock
5 mg	$483	In Stock
10 mg	$692	In Stock
25 mg	$1,080	In Stock
50 mg	$1,490	In Stock

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COA

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

Alias

L-Laudanosine, L-(+)-Laudanosine, (+)-Laudanosine

Chemical Properties

Molecular Weight	357.44
Formula	C₂₁H₂₇NO₄
Cas No.	2688-77-9
Smiles	C([C@H]1C=2C(=CC(OC)=C(OC)C2)CCN1C)C3=CC(OC)=C(OC)C=C3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 40 mg/mL (111.91 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7977 mL	13.9884 mL	27.9767 mL	139.8836 mL
5 mM	0.5595 mL	2.7977 mL	5.5953 mL	27.9767 mL
10 mM	0.2798 mL	1.3988 mL	2.7977 mL	13.9884 mL
20 mM	0.1399 mL	0.6994 mL	1.3988 mL	6.9942 mL
50 mM	0.0560 mL	0.2798 mL	0.5595 mL	2.7977 mL
100 mM	0.0280 mL	0.1399 mL	0.2798 mL	1.3988 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NSC 35045