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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $29 | In Stock | |
100 mg | $39 | In Stock | |
500 mg | $98 | In Stock | |
1 mL x 10 mM (in DMSO) | $29 | In Stock |
Description | TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS. |
In vivo | TRIM is a poor inhibitor of bovine aortic endothelial NOS with an IC50 of 1057.5 microM. TRIM (10-50 mg kg-1) administered i.p. exhibits dose-related antinociceptive activity in the mouse (assessed as inhibition of late phase formalin-induced hindpaw licking behaviour) with an ED50 of 85.8 mumol kg-1. In contrast, TRIM (50 mg kg-1, i.p.) failed to influence mean arterial blood pressure in the urethane-anaesthetized mouse[1]. |
Alias | 1-(2-Trifluoromethylphenyl)imidazole |
Molecular Weight | 212.17 |
Formula | C10H7F3N2 |
Cas No. | 25371-96-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 2.12 mg/mL (10 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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