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Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) exhibits moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $156 | In Stock | |
5 mg | $333 | In Stock | |
10 mg | $568 | In Stock | |
25 mg | $897 | In Stock | |
50 mg | $1,180 | In Stock | |
1 mL x 10 mM (in DMSO) | $388 | In Stock |
Description | Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) exhibits moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro. |
Targets&IC50 | PTP1B (human):IC50: 26.6 μM |
In vitro | A new lignan glycoside, named 1,5-dihydroxypinoresinol-4'-O-beta-d-glucopyranoside (1), has been isolated from the EtOH extract of the roots of Saussurea lappa, together with twenty known compounds: (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside (2), fraxiresinol-4'-O-beta-D-glucopyranoside (3), (-)-olivil-4''-O-beta-D-glucopyranoside (4), 4-allyl-2,6-dimethoxybenzene-1-O-beta-D-glucopyranoside, syringin, costunolide-15-O-beta-D-glucopyranoside, chlorogenic acid, Aloe-emodin-8-O-beta-D-glucopyranoside (5), rhein-8-O-beta-D-glucopyranoside (6), chrysophanol (7), emodin, dehydrocostus lactone, costunolide, beta-costic acid, reynosin, arbusculin A, alpha-cyclocostunolide, beta-cyclocostunolide, santamarine and magnolialide. |
Alias | Aloe-emodin-8-O-beta-D-glucopyranoside |
Molecular Weight | 432.38 |
Formula | C21H20O10 |
Cas No. | 33037-46-6 |
Smiles | OC[C@H]1O[C@@H](Oc2cccc3C(=O)c4cc(CO)cc(O)c4C(=O)c23)[C@H](O)[C@@H](O)[C@@H]1O |
Relative Density. | 1.673 g/cm3 at 20℃ |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 9 mg/mL (20.81 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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