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Adenosine amine congener

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Purity:98.29%

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COA HPLC HNMR

Adenosine amine congener

Catalog No. T7683Cas No. 96760-69-9

Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.

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Pack Size	Price	Availability
1 mg	$67	In Stock
5 mg	$163	In Stock
10 mg	$247	In Stock
25 mg	$447	In Stock
50 mg	$659	In Stock
100 mg	$939	In Stock
1 mL x 10 mM (in DMSO)	$259	In Stock

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Product Introduction

Bioactivity

Description	Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.
In vivo	Adenosine amine congener (ADAC) was most effective in the first 24 hours after noise exposure at doses >50 μg/kg, providing up to 21 dB protection (averaged across 8-28 kHz). Pharmacokinetic studies demonstrated a short (5 min) half-life of ADAC in plasma after intravenous administration without detection of degradation products.
Animal Research	Adenosine amine congener (ADAC)??(25-300 μg/kg) was administered intraperitoneally to Wistar rats (8-10 weeks old) at intervals (6-72 hours) after exposure to traumatic noise (8-16 kHz, 110 dB sound pressure level, 2 hours). Hearing sensitivity was assessed using auditory brainstem responses (ABR) before and 12 days after noise exposure. Pharmacokinetic studies investigated ADAC concentrations in plasma after systemic (intravenous) administration[1].
Alias	ADAC

Chemical Properties

Molecular Weight	576.6
Formula	C28H32N8O6
Cas No.	96760-69-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 31.25 mg/mL (54.20 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7343 mL	8.6715 mL	17.3430 mL	86.7152 mL
5 mM	0.3469 mL	1.7343 mL	3.4686 mL	17.3430 mL
10 mM	0.1734 mL	0.8672 mL	1.7343 mL	8.6715 mL
20 mM	0.0867 mL	0.4336 mL	0.8672 mL	4.3358 mL
50 mM	0.0347 mL	0.1734 mL	0.3469 mL	1.7343 mL

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In Vivo Formulation Calculator (Clear solution)

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

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