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Adenosine amine congener
🥰Excellent
Catalog No. T7683Cas No. 96760-69-9
Alias ADAC
Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.
Adenosine amine congener
🥰Excellent
Purity: 97.86%
Catalog No. T7683Alias ADACCas No. 96760-69-9
Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $67 | In Stock | |
| 5 mg | $163 | In Stock | |
| 10 mg | $247 | In Stock | |
| 25 mg | $447 | In Stock | |
| 50 mg | $659 | In Stock | |
| 100 mg | $939 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $259 | In Stock |
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Purity:97.86%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,. |
| In vivo | Adenosine amine congener (ADAC) was most effective in the first 24 hours after noise exposure at doses >50 μg/kg, providing up to 21 dB protection (averaged across 8-28 kHz). Pharmacokinetic studies demonstrated a short (5 min) half-life of ADAC in plasma after intravenous administration without detection of degradation products. |
| Animal Research | Adenosine amine congener (ADAC)??(25-300 μg/kg) was administered intraperitoneally to Wistar rats (8-10 weeks old) at intervals (6-72 hours) after exposure to traumatic noise (8-16 kHz, 110 dB sound pressure level, 2 hours). Hearing sensitivity was assessed using auditory brainstem responses (ABR) before and 12 days after noise exposure. Pharmacokinetic studies investigated ADAC concentrations in plasma after systemic (intravenous) administration[1]. |
| Alias | ADAC |
| Molecular Weight | 576.6 |
| Formula | C28H32N8O6 |
| Cas No. | 96760-69-9 |
| Smiles | NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4n(cnc34)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)cc1 |
| Relative Density. | 1.56 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 31.25 mg/mL (54.20 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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