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Epibetulinic acid

Catalog No. T2S0765Cas No. 38736-77-5

Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.

Epibetulinic acid

Epibetulinic acid

Purity: 99.02%
Catalog No. T2S0765Cas No. 38736-77-5
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$118In Stock
10 mg$178In Stock
25 mg$297In Stock
50 mg$441In Stock
100 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$141In Stock
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Purity:99.02%
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Product Introduction

Bioactivity
Description
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.
Targets&IC50
NO:0.7 μM (IC50), PGE2:0.6 μM (IC50)
Chemical Properties
Molecular Weight456.7
FormulaC30H48O3
Cas No.38736-77-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (109.48 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1896 mL10.9481 mL21.8962 mL109.4811 mL
5 mM0.4379 mL2.1896 mL4.3792 mL21.8962 mL
10 mM0.2190 mL1.0948 mL2.1896 mL10.9481 mL
20 mM0.1095 mL0.5474 mL1.0948 mL5.4741 mL
50 mM0.0438 mL0.2190 mL0.4379 mL2.1896 mL
100 mM0.0219 mL0.1095 mL0.2190 mL1.0948 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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