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6-Formylpterin (Pterin-6-aldehyde) is an inhibitor of Xanthine Oxidase (Ki ~0.6 nM) with potent neuroprotective effects against transient IRI in gerbils.6-Formylpterin induces intracellular ROS generation in HL-60 cells as well as apoptosis ( 6-Formylpterin inhibits the expression of iNOS, produces hydrogen peroxide intracellularly and restores the impaired bactericidal activity of human neutrophils.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 33 € | In Stock | |
5 mg | 75 € | In Stock | |
10 mg | 113 € | In Stock | |
25 mg | 186 € | In Stock | |
50 mg | 274 € | In Stock | |
100 mg | 407 € | In Stock |
Description | 6-Formylpterin (Pterin-6-aldehyde) is an inhibitor of Xanthine Oxidase (Ki ~0.6 nM) with potent neuroprotective effects against transient IRI in gerbils.6-Formylpterin induces intracellular ROS generation in HL-60 cells as well as apoptosis ( 6-Formylpterin inhibits the expression of iNOS, produces hydrogen peroxide intracellularly and restores the impaired bactericidal activity of human neutrophils. |
In vitro | 6-Formylpterin (0.5, 1, and 2 mM; 3h; HL-60 cells, Jurkat cells) Induced apoptosis in HL-60 cells, and Inhibited Fas-mediated apoptosis in Jurkat cells.[1] 6-Formylpterin (2 mM) produces ROS in HL-60 cells.[1] |
Alias | Pterin-6-aldehyde, 6 Formylpterin |
Molecular Weight | 191.15 |
Formula | C7H5N5O2 |
Cas No. | 712-30-1 |
Smiles | Nc1nc(O)c2nc(C=O)cnc2n1 |
Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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