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Ermanin
🥰Excellent
Catalog No. TN1622Cas No. 20869-95-8
Ermanin, a flavonoid isolated from Tanacetum microphyllum, inhibits platelet aggregation and exhibits anti-tuberculosis, anti-viral/bacterial, and potential anti-HIV-1 activities. It has anti-inflammatory properties through the inhibition of iNOS and COX-2 expression and is effective at lower concentrations in inhibiting Dione juno larvae.
Ermanin
🥰Excellent
Purity: 98.46%
Catalog No. TN1622Cas No. 20869-95-8
Ermanin, a flavonoid isolated from Tanacetum microphyllum, inhibits platelet aggregation and exhibits anti-tuberculosis, anti-viral/bacterial, and potential anti-HIV-1 activities. It has anti-inflammatory properties through the inhibition of iNOS and COX-2 expression and is effective at lower concentrations in inhibiting Dione juno larvae.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $186 | In Stock | |
| 5 mg | $460 | In Stock | |
| 10 mg | $676 | In Stock | |
| 25 mg | $1,060 | In Stock | |
| 50 mg | $1,430 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $470 | In Stock |
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Purity:98.46%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ermanin, a flavonoid isolated from Tanacetum microphyllum, inhibits platelet aggregation and exhibits anti-tuberculosis, anti-viral/bacterial, and potential anti-HIV-1 activities. It has anti-inflammatory properties through the inhibition of iNOS and COX-2 expression and is effective at lower concentrations in inhibiting Dione juno larvae. |
| In vitro | Ermanin (3.25, 6.25, 12.5, and 25 μM) on modulation of LPS-induced iNOS and COX-2 expression in RAW 264.7 cells. Ermanin decreased LPS-induced COX-2 and iNOS expression by 94 ± 0.5% and 94 ± 0.5% with IC50 were 1.68 μM and 6.70 μM, respectively.[1] |
| Molecular Weight | 314.29 |
| Formula | C17H14O6 |
| Cas No. | 20869-95-8 |
| Smiles | O(C)C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC=C(OC)C=C3 |
| Relative Density. | 1.46 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100mg/mL（318.18 mM）  | |||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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