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D-myo-Inositol-1,4,5-triphosphate tripotassium

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Catalog No. T35934Cas No. 141611-11-2
Alias Ins(1,4,5)-P3 tripotassium, Inositol 1,4,5-trisphosphate tripotassium

D-myo-Inositol-1,4,5-triphosphate tripotassium (Ins(1,4,5)-P3 tripotassium) is a second messenger in cellular signal transduction that triggers Ca2+ mobilization.

D-myo-Inositol-1,4,5-triphosphate tripotassium

D-myo-Inositol-1,4,5-triphosphate tripotassium

😃Good
Catalog No. T35934Alias Ins(1,4,5)-P3 tripotassium, Inositol 1,4,5-trisphosphate tripotassiumCas No. 141611-11-2
D-myo-Inositol-1,4,5-triphosphate tripotassium (Ins(1,4,5)-P3 tripotassium) is a second messenger in cellular signal transduction that triggers Ca2+ mobilization.
Pack SizePriceAvailabilityQuantity
100 μg$7835 days
500 μg$18335 days
1 mg$32335 days
5 mg$1,38035 days
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Product Introduction

Bioactivity
Description
D-myo-Inositol-1,4,5-triphosphate tripotassium (Ins(1,4,5)-P3 tripotassium) is a second messenger in cellular signal transduction that triggers Ca2+ mobilization.
In vitro
D-myo-Inositol-1,4,5-triphosphate tripotassium inhibits phosphatidylinositol-specific phospholipase C-delta 1 (PLC-delta 1) and phosphatidylcholine (PC) and phosphatidylinositol 4, 5-diphosphate (PIP2) consists of a combination of bilayer membranes. [1]
AliasIns(1,4,5)-P3 tripotassium, Inositol 1,4,5-trisphosphate tripotassium
Chemical Properties
Molecular Weight534.37
FormulaC6H12K3O15P3
Cas No.141611-11-2
SmilesO=P([O-])(O)O[C@H]1[C@@H]([C@H]([C@H]([C@H]([C@@H]1O)OP(O)([O-])=O)O)O)OP(O)([O-])=O.[K+].[K+].[K+]
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
PBS: 30 mg/mL (56.14 mM), Sonication is recommended.
PBS (pH 7.2): >50 mg/mL
Solution Preparation Table
PBS
1mg5mg10mg50mg
1 mM1.8714 mL9.3568 mL18.7136 mL93.5681 mL
5 mM0.3743 mL1.8714 mL3.7427 mL18.7136 mL
10 mM0.1871 mL0.9357 mL1.8714 mL9.3568 mL
20 mM0.0936 mL0.4678 mL0.9357 mL4.6784 mL
50 mM0.0374 mL0.1871 mL0.3743 mL1.8714 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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