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17-phenyl trinor Prostaglandin F2α methyl amide

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Catalog No. T37944Cas No. 155206-01-2
Alias 17-phenyl trinor Prostaglandin F2α methyl amide

17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.

17-phenyl trinor Prostaglandin F2α methyl amide

17-phenyl trinor Prostaglandin F2α methyl amide

😃Good
Catalog No. T37944Alias 17-phenyl trinor Prostaglandin F2α methyl amideCas No. 155206-01-2
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.
Pack SizePriceAvailabilityQuantity
1 mgInquiry35 days
5 mgInquiry35 days
10 mgInquiry35 days
50 mgInquiry35 days
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Product Introduction

Bioactivity
Description
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.
Alias17-phenyl trinor Prostaglandin F2α methyl amide
Chemical Properties
Molecular Weight401.547
FormulaC24H35NO4
Cas No.155206-01-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: 25 mg/mL (62.26 mM), Sonication is recommended.
PBS (pH 7.2): 300 μg/mL, Sonication is recommended.
Ethanol: 50 mg/mL (124.52 mM), Sonication is recommended.
Acetonitrile: 3 mg/mL (7.47 mM), Sonication is recommended.
DMSO: 25 mg/mL (62.26 mM), Sonication is recommended.
Solution Preparation Table
Acetonitrile/DMF/DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.4904 mL12.4518 mL24.9037 mL124.5184 mL
5 mM0.4981 mL2.4904 mL4.9807 mL24.9037 mL
DMF/DMSO/Ethanol
1mg5mg10mg50mg
10 mM0.2490 mL1.2452 mL2.4904 mL12.4518 mL
20 mM0.1245 mL0.6226 mL1.2452 mL6.2259 mL
50 mM0.0498 mL0.2490 mL0.4981 mL2.4904 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Keywords

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