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PRDX1-IN-1
🥰Excellent
Catalog No. T78785
PRDX1-IN-1 is a selective and potent PRDX1 inhibitor with potential anti-inflammatory and anticancer activity for the study of breast and esophageal cancer.
PRDX1-IN-1
🥰Excellent
Purity: 98.04%
Catalog No. T78785
PRDX1-IN-1 is a selective and potent PRDX1 inhibitor with potential anti-inflammatory and anticancer activity for the study of breast and esophageal cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $599 | In Stock |
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Purity:98.04%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | PRDX1-IN-1 is a selective and potent PRDX1 inhibitor with potential anti-inflammatory and anticancer activity for the study of breast and esophageal cancer. |
| In vitro | PRDX1-IN-1 (0.5-10 μM; 48 hours) was able to inhibit the proliferative activity of lung cancer cell lines (LTEP-a-2 and H1975), and human breast cancer cell line (MDA-MB-231)[1]. |
| In vivo | PRDX1-IN-1 (0.5 or 1 mg/kg; once daily for 19 days; intraperitoneal injection) treatment in C57BL/6J male mice inoculated with Lewis cells (lung cancer) was found to significantly inhibit tumor growth and induce morphological changes in tumor cells, including cell aggregation, contraction, and nuclear chromatin margination[1]. |
| Molecular Weight | 713.95 |
| Formula | C46H55N3O4 |
| Smiles | O=C(OC1=C(C)C2=CC=C([C@](CC[C@]3(C)[C@@]4([H])C[C@@](C(NCC5=C(C)N=C(C)C(C)=N5)=O)(C)CC3)(C)[C@@]4(C)CC6)[C@]6(C)C2=CC1=O)/C=C/C7=CC=CC=C7 |
Storage & Solubility Information
| Storage | store at low temperature | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (112.05 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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