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DL-Glyceraldehyde

Catalog No. T4918Cas No. 56-82-6
Alias Glyceric aldehyde

DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, DL-Glyceraldehyde can be a cytotoxin and a mutagen. A cytotoxin is a compound that kills cells. A mutagen is a compound that causes mutations in DNA. DL-Glyceraldehyde is a highly reactive compound that can modify and cross-link proteins. DL-Glyceraldehyde modified proteins appear to be cytotoxic, depress intracellular glutathione levels, and induce reactive oxygen species (ROS) production (PMID: 14981296 ). DL-Glyceraldehyde has been shown to cause chromosome damage to human cells in culture and is mutagenic in the Ames bacterial test.

DL-Glyceraldehyde

DL-Glyceraldehyde

Purity: 95.88%
Catalog No. T4918Alias Glyceric aldehydeCas No. 56-82-6
DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, DL-Glyceraldehyde can be a cytotoxin and a mutagen. A cytotoxin is a compound that kills cells. A mutagen is a compound that causes mutations in DNA. DL-Glyceraldehyde is a highly reactive compound that can modify and cross-link proteins. DL-Glyceraldehyde modified proteins appear to be cytotoxic, depress intracellular glutathione levels, and induce reactive oxygen species (ROS) production (PMID: 14981296 ). DL-Glyceraldehyde has been shown to cause chromosome damage to human cells in culture and is mutagenic in the Ames bacterial test.
Pack SizePriceAvailabilityQuantity
10 mg$47In Stock
25 mg$76In Stock
50 mg$112In Stock
100 mg$165In Stock
200 mg$245In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:95.88%
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Product Introduction

Bioactivity
Description
DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, DL-Glyceraldehyde can be a cytotoxin and a mutagen. A cytotoxin is a compound that kills cells. A mutagen is a compound that causes mutations in DNA. DL-Glyceraldehyde is a highly reactive compound that can modify and cross-link proteins. DL-Glyceraldehyde modified proteins appear to be cytotoxic, depress intracellular glutathione levels, and induce reactive oxygen species (ROS) production (PMID: 14981296 ). DL-Glyceraldehyde has been shown to cause chromosome damage to human cells in culture and is mutagenic in the Ames bacterial test.
Targets&IC50
Aldose reductase:10 nM(Human)
AliasGlyceric aldehyde
Chemical Properties
Molecular Weight90.08
FormulaC3H6O3
Cas No.56-82-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.4 mg/mL (48.85 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM11.1012 mL55.5062 mL111.0124 mL555.0622 mL
5 mM2.2202 mL11.1012 mL22.2025 mL111.0124 mL
10 mM1.1101 mL5.5506 mL11.1012 mL55.5062 mL
20 mM0.5551 mL2.7753 mL5.5506 mL27.7531 mL

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