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Limonene
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Catalog No. T75431Cas No. 138-86-3
Alias Dipentene, (±)-α-Limonene, (±)-Limonene
Limonene (Dipentene) is a monoterpene found in citrus plants such as lemon, orange, and grape, widely used in cosmetics and household products as a fragrance, with antimicrobial, antiproliferative, antioxidant, and anti-inflammatory properties.
Limonene
🥰Excellent
Catalog No. T75431Alias Dipentene, (±)-α-Limonene, (±)-LimoneneCas No. 138-86-3
Limonene (Dipentene) is a monoterpene found in citrus plants such as lemon, orange, and grape, widely used in cosmetics and household products as a fragrance, with antimicrobial, antiproliferative, antioxidant, and anti-inflammatory properties.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Limonene (Dipentene) is a monoterpene found in citrus plants such as lemon, orange, and grape, widely used in cosmetics and household products as a fragrance, with antimicrobial, antiproliferative, antioxidant, and anti-inflammatory properties. |
| In vitro | Limonene exerts anti-inflammatory effects by reducing pro-inflammatory cytokines (TNF-α, IL-1β, COX-2), inhibiting TLR4/NF-κB/AP-1 but not the IRF3 signaling pathway, and regulating oxidative stress through Nrf2 activation. [1] Limonene treatment inhibits UVB-induced α-MSH secretion and then suppresses melanocortin (POMC) by inhibiting p53 transcriptional activation. [2] |
| In vivo | Limonene (100 and 200 mg/kg, orally administered) in LPS mouse models mitigated the decline in renal function due to LPS induction, resulting in reduced serum urea and creatinine levels in mice. [1] Limonene (20 mg/kg, intrabitoneally administered) reduced serum and brain nitrite levels and decreased the expression of IL-1β and TNF-α in the hippocampus of MS-stressed mice. [3] |
| Alias | Dipentene, (±)-α-Limonene, (±)-Limonene |
| Molecular Weight | 136.23 |
| Formula | C10H16 |
| Cas No. | 138-86-3 |
| Smiles | C=C(C)C1CC=C(C)CC1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 80.00 mg/mL (587.24 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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