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Camalexin

Camalexin
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Purity:99.84%
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Camalexin

Catalog No. T10668Cas No. 135531-86-1
Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production.
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Pack SizePriceAvailabilityQuantity
5 mg$64In Stock
10 mg$105In Stock
25 mg$206In Stock
50 mg$346In Stock
1 mL x 10 mM (in DMSO)$64In Stock
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Product Introduction

Bioactivity
Description
Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production.
In vitro
Camalexin shows antiproliferative activity against a human breast cancer cell line. For the oomycetes, Phytophthora and Pythium Nep1-like proteins are the initial triggers of Camalexin synthesis and formation of ROS. ROS appear to be of general relevance for Camalexin formation. In a screen for enhanced susceptibility to Alternaria brassicicola the esa1 mutant is identified, which shows delayed Camalexin induction. Particularly in response to ROS inducing agents reduced Camalexin levels are synthesized. This crucial role for ESA1 is confirmed by the inability of esa1 mutants to synthesize Camalexin in response to Leptosphaeria maculans [2].
Chemical Properties
Molecular Weight200.26
FormulaC11H8N2S
Cas No.135531-86-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 120 mg/mL (599.22 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.9935 mL24.9675 mL49.9351 mL249.6754 mL
5 mM0.9987 mL4.9935 mL9.9870 mL49.9351 mL
10 mM0.4994 mL2.4968 mL4.9935 mL24.9675 mL
20 mM0.2497 mL1.2484 mL2.4968 mL12.4838 mL
50 mM0.0999 mL0.4994 mL0.9987 mL4.9935 mL
100 mM0.0499 mL0.2497 mL0.4994 mL2.4968 mL

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