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Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $138 | 35 days | |
1 mg | $253 | 35 days | |
5 mg | $1,050 | 35 days | |
10 mg | $1,800 | 35 days |
Description | Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid. |
Alias | 16-phenoxy tetranor Prostaglandin F2α isopropyl ester |
Molecular Weight | 432.557 |
Formula | C25H36O6 |
Cas No. | 130209-78-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | PBS (pH 7.2): 0.5 mg/mL (1.16 mM), Sonication is recommended. DMF: 100 mg/mL (231.18 mM), Sonication is recommended. Ethanol: 100 mg/mL (231.18 mM), Sonication is recommended. DMSO: 100 mg/mL (231.18 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
PBS (pH 7.2)/DMF/Ethanol/DMSO
DMF/Ethanol/DMSO
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