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Epieriocalyxin A

Catalog No. TN3967Cas No. 191545-24-1

Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.

Epieriocalyxin A

Epieriocalyxin A

Purity: 97.00%
Catalog No. TN3967Cas No. 191545-24-1
Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.
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1 mg$216In Stock
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Purity:97.00%
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Product Introduction

Bioactivity
Description
Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.
In vitro
Epieriocalyxin A (EpiA), a diterpenoid isolated from I. eriocalyx, suppressed Caco-2 colon cancer cell growth. EpiA induced annexin V flipping in the cell membrane and DNA fragment. We also showed that EpiA induced the generation of ROS in cells, as well as damage of the mitochondrial membrane. Western blot results showed that both JNK and ERK1/2 activation was decreased after EpiA treatment in a dose-dependent manner. EpiA increased the expression of caspase 3 and Bax and decreased Bcl2 expression.
Chemical Properties
Molecular Weight344.4
FormulaC20H24O5
Cas No.191545-24-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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