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Pyridinium bisretinoid A2E

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Catalog No. T74051Cas No. 173449-96-2
Alias A2E

Pyridinium bisretinoid A2E (A2E) is a fluorescent chromophore isolated from lipofuscin in retinal pigment epithelium, a lipophilic cation and weak photosensitizer with cytotoxicity. A2E promotes apoptosis under blue light exposure and induces autophagy under photoactivation, damaging membrane integrity in a concentration-dependent manner.

Pyridinium bisretinoid A2E

Pyridinium bisretinoid A2E

🥰Excellent
Catalog No. T74051Alias A2ECas No. 173449-96-2
Pyridinium bisretinoid A2E (A2E) is a fluorescent chromophore isolated from lipofuscin in retinal pigment epithelium, a lipophilic cation and weak photosensitizer with cytotoxicity. A2E promotes apoptosis under blue light exposure and induces autophagy under photoactivation, damaging membrane integrity in a concentration-dependent manner.
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1 mg$829 In Stock
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Product Introduction

Bioactivity
Description
Pyridinium bisretinoid A2E (A2E) is a fluorescent chromophore isolated from lipofuscin in retinal pigment epithelium, a lipophilic cation and weak photosensitizer with cytotoxicity. A2E promotes apoptosis under blue light exposure and induces autophagy under photoactivation, damaging membrane integrity in a concentration-dependent manner.
AliasA2E
Chemical Properties
Molecular Weight592.92
FormulaC42H58NO
Cas No.173449-96-2
SmilesC(CO)[N+]=1C(/C=C(/C=C/C=C(/C=C/C=2C(C)(C)CCCC2C)\C)\C)=CC(/C=C/C=C(/C=C/C=3C(C)(C)CCCC3C)\C)=CC1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 120 mg/mL (202.39 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6866 mL8.4328 mL16.8657 mL84.3284 mL
5 mM0.3373 mL1.6866 mL3.3731 mL16.8657 mL
10 mM0.1687 mL0.8433 mL1.6866 mL8.4328 mL
20 mM0.0843 mL0.4216 mL0.8433 mL4.2164 mL
50 mM0.0337 mL0.1687 mL0.3373 mL1.6866 mL
100 mM0.0169 mL0.0843 mL0.1687 mL0.8433 mL

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