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Pyridinium bisretinoid A2E (A2E) is a fluorescent chromophore isolated from lipofuscin in retinal pigment epithelium, a lipophilic cation and weak photosensitizer with cytotoxicity. A2E promotes apoptosis under blue light exposure and induces autophagy under photoactivation, damaging membrane integrity in a concentration-dependent manner.
Pack Size | Price | Availability | Quantity |
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1 mg | $829 | In Stock |
Description | Pyridinium bisretinoid A2E (A2E) is a fluorescent chromophore isolated from lipofuscin in retinal pigment epithelium, a lipophilic cation and weak photosensitizer with cytotoxicity. A2E promotes apoptosis under blue light exposure and induces autophagy under photoactivation, damaging membrane integrity in a concentration-dependent manner. |
Alias | A2E |
Molecular Weight | 592.92 |
Formula | C42H58NO |
Cas No. | 173449-96-2 |
Smiles | C(CO)[N+]=1C(/C=C(/C=C/C=C(/C=C/C=2C(C)(C)CCCC2C)\C)\C)=CC(/C=C/C=C(/C=C/C=3C(C)(C)CCCC3C)\C)=CC1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 120 mg/mL (202.39 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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