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Pyridinium bisretinoid A2E TFA
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Catalog No. T78404Cas No. 1821308-73-9
Alias A2E TFA
Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2].
Pyridinium bisretinoid A2E TFA
😃Good
Catalog No. T78404Alias A2E TFACas No. 1821308-73-9
Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2].
| Pack Size | Price | Availability | Quantity |
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| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2]. |
| In vitro | Exposure to light induces pyridinium bisretinoid A2E (A2E) to transform into at least two products. One of them is epoxy-A2E, which is hydrophilic and can migrate from membranes into aqueous solutions. The other product is an unidentified hydrophobic substance [3]. |
| Alias | A2E TFA |
| Molecular Weight | 705.93 |
| Formula | C44H58F3NO3 |
| Cas No. | 1821308-73-9 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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