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15(S)-15-methyl Prostaglandin D2

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Catalog No. T36153Cas No. 85280-90-6
Alias 15(S)-15-methyl Prostaglandin D2

15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. Unlike PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction, increases systemic blood pressure, and exhibits significantly reduced inhibitory activity on ADP-induced platelet aggregation. It also demonstrates strong antifertility activity in hamsters, being 200-fold more potent than PGD2.

15(S)-15-methyl Prostaglandin D2
Other Forms of 15(S)-15-methyl Prostaglandin D2:
15(R)-15-methyl Prostaglandin D2T37264210978-26-0
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15(S)-15-methyl Prostaglandin D2

😃Good
Catalog No. T36153Alias 15(S)-15-methyl Prostaglandin D2Cas No. 85280-90-6
15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. Unlike PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction, increases systemic blood pressure, and exhibits significantly reduced inhibitory activity on ADP-induced platelet aggregation. It also demonstrates strong antifertility activity in hamsters, being 200-fold more potent than PGD2.
Pack SizePriceAvailabilityQuantity
500 μg$18335 days
1 mg$34535 days
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Product Introduction

Bioactivity
Description
15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. Unlike PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction, increases systemic blood pressure, and exhibits significantly reduced inhibitory activity on ADP-induced platelet aggregation. It also demonstrates strong antifertility activity in hamsters, being 200-fold more potent than PGD2.
Alias15(S)-15-methyl Prostaglandin D2
Chemical Properties
Molecular Weight366.49
FormulaC21H34O5
Cas No.85280-90-6
Relative Density.1.134g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: >100 mg/mL (from PGD2)
PBS (pH 7.2): >5 mg/mL (from PGD2)
DMSO: >50 mg/mL (from PGD2)
Ethanol: >75 mg/mL (from PGD2)

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

15(S)-15-methyl Prostaglandin D-21515-methyl Prostaglandin D215(S) 15 methyl Prostaglandin D215(S)15methyl Prostaglandin D2
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