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SFI003

🥰Excellent
Catalog No. T72068Cas No. 2361332-90-1

SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in CRC cells through the SRSF3 / DHCR24 / reactive oxygen species (ROS) axis.

SFI003

SFI003

🥰Excellent
Purity: 99.37%
Catalog No. T72068Cas No. 2361332-90-1
SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in CRC cells through the SRSF3 / DHCR24 / reactive oxygen species (ROS) axis.
Pack SizePriceAvailabilityQuantity
1 mg$84In Stock
5 mg$210In Stock
10 mg$320In Stock
25 mg$550In Stock
50 mg$792In Stock
100 mg$1,080In Stock
500 mg$2,190In Stock
1 mL x 10 mM (in DMSO)$228In Stock
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Purity:99.37%
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Product Introduction

Bioactivity
Description
SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in CRC cells through the SRSF3 / DHCR24 / reactive oxygen species (ROS) axis.
Chemical Properties
Molecular Weight363.44
FormulaC19H17N5OS
Cas No.2361332-90-1
SmilesC(=N\NC1=NC(=CS1)C2=CC=C(OC)C=C2)(\C)/C=3NC=4C(N3)=CC=CC4
Relative Density.1.36 g/cm3 (Predicted)
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (137.57 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7515 mL13.7574 mL27.5149 mL137.5743 mL
5 mM0.5503 mL2.7515 mL5.5030 mL27.5149 mL
10 mM0.2751 mL1.3757 mL2.7515 mL13.7574 mL
20 mM0.1376 mL0.6879 mL1.3757 mL6.8787 mL
50 mM0.0550 mL0.2751 mL0.5503 mL2.7515 mL
100 mM0.0275 mL0.1376 mL0.2751 mL1.3757 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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