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Dp3-Sam chloride
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Catalog No. TN1566Cas No. 53158-73-9
Alias Delphinidin-3-sambubioside chloride
Dp3-Sam chloride (Delphinidin-3-sambubioside chloride) is an anthocyanin from Hibiscus acetosella (Cranberry Hibiscus) with anti-inflammatory, antioxidant, and anticancer activities.Dp3-Sam chloride inhibits LPS-induced inflammation, and inhibits LPS-induced inflammation. Dp3-Sam chloride inhibits LPS-induced inflammatory factor release, down-regulates the NF-κB pathway, and inhibits MEK1/2-ERK1/2 signaling.Dp3-Sam chloride induces apoptosis in human leukemia cells through the mitochondrial pathway mediated by reactive oxygen species.
Dp3-Sam chloride
😃Good
Catalog No. TN1566Alias Delphinidin-3-sambubioside chlorideCas No. 53158-73-9
Dp3-Sam chloride (Delphinidin-3-sambubioside chloride) is an anthocyanin from Hibiscus acetosella (Cranberry Hibiscus) with anti-inflammatory, antioxidant, and anticancer activities.Dp3-Sam chloride inhibits LPS-induced inflammation, and inhibits LPS-induced inflammation. Dp3-Sam chloride inhibits LPS-induced inflammatory factor release, down-regulates the NF-κB pathway, and inhibits MEK1/2-ERK1/2 signaling.Dp3-Sam chloride induces apoptosis in human leukemia cells through the mitochondrial pathway mediated by reactive oxygen species.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $611 | 7-10 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Dp3-Sam chloride (Delphinidin-3-sambubioside chloride) is an anthocyanin from Hibiscus acetosella (Cranberry Hibiscus) with anti-inflammatory, antioxidant, and anticancer activities.Dp3-Sam chloride inhibits LPS-induced inflammation, and inhibits LPS-induced inflammation. Dp3-Sam chloride inhibits LPS-induced inflammatory factor release, down-regulates the NF-κB pathway, and inhibits MEK1/2-ERK1/2 signaling.Dp3-Sam chloride induces apoptosis in human leukemia cells through the mitochondrial pathway mediated by reactive oxygen species. |
| In vitro | Dp3-Sam chloride (50-200 μM, 30 min) inhibits LPS-induced iNOS expression, suppresses the phosphorylation of ERK1/2 and MEK1/2, and downregulates the NF-κB signaling pathway in RAW264.7 cells[1]. Dp3-Sam chloride (24 h) inhibits HL-60 cells proliferation by inducing apoptosis (IC50 of 75 μM).[2] Dp3-Sam chloride (100-200 µg/mL, 24 h) decreases intracellular TG levels and lipid accumulation in oleic acid-treated HepG2 cells.[2] |
| In vivo | Dp3-Sam chloride (15 μmol/kg; i.p.; mouse) reduced the LPS-induced paw thickness and decreased the edema by 89.3%.[1] Dp3-Sam chloride (30 mg/kg body; oral gavage; daily for eight weeks) decreases lipid accumulation in HFD rats and decreases LPS-induced serum IL-6, MCP-1, and TNF-α levels.[3] |
| Alias | Delphinidin-3-sambubioside chloride |
| Molecular Weight | 632.95 |
| Formula | C26H29ClO16 |
| Cas No. | 53158-73-9 |
| Smiles | O(C=1C(=[O+]C2=C(C1)C(O)=CC(O)=C2)C3=CC(O)=C(O)C(O)=C3)[C@H]4[C@H](O[C@H]5[C@H](O)[C@@H](O)[C@H](O)CO5)[C@@H](O)[C@H](O)[C@@H](CO)O4.[Cl-] |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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