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Bacoside A3

Bacoside A3
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Bacoside A3

Catalog No. TN1425Cas No. 157408-08-7
Bacoside A3 is one of the components of Bacopa monnieri (L.) Wettst. bacoside A with antioxidant potential. Bacoside A3 shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.
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Pack SizePriceAvailabilityQuantity
1 mg$68In Stock
5 mg$160In Stock
10 mg$235In Stock
1 mL x 10 mM (in DMSO)$268In Stock
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Product Introduction

Bioactivity
Description
Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.
In vitro
The cytoprotective effects of individual bacoside A components were evaluated towards oxidative stressed neuronal cells. Bacoside A was screened for neuronal cell viability (MTT assay) and change in intracellular reactive oxygen species (ROS), anti-apoptotic properties and mitochondrial membrane potential (MMP) using fluorescence microscopy. Different bacoside A components showed decrease in N2a cell viability below 100 (%) after bacoside A concentration of 0.4 mg/ml. Further, cytoprotective effect of optimized dose of bacoside A was analysed for alleviating oxidative stressed, apoptosis and MMP in H2 O2 stressed neuronal cells. Results showed increase in MMP, and decrease in apoptotic induction, without much change in nuclear integrity in stressed neuronal cells. Results showed Bacoside A3 and bacopaside II have comparatively higher cytoprotective ability whilst isomer of bacopasponin C, bacopasaponin C and mixture showed comparatively less response[1]
Chemical Properties
Molecular Weight929.1
FormulaC47H76O18
Cas No.157408-08-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 60 mg/mL (64.58 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.0763 mL5.3816 mL10.7631 mL53.8155 mL
5 mM0.2153 mL1.0763 mL2.1526 mL10.7631 mL
10 mM0.1076 mL0.5382 mL1.0763 mL5.3816 mL
20 mM0.0538 mL0.2691 mL0.5382 mL2.6908 mL
50 mM0.0215 mL0.1076 mL0.2153 mL1.0763 mL

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