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8-iso-15-keto Prostaglandin F2β

Catalog No. T36167Cas No. 1621482-36-7

8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin. It is one of 64 possible isomers of PGF2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2β exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF2β moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8-iso PGE1, 8-iso PGE2, or 8-iso PGF2α. 8-iso-15-keto PGF2β is a potential metabolite of 8-iso PGF2β via the 15-hydroxy PG dehydrogenase pathway. There are no published reports on the formation or biological activity of 8-iso-15-keto PGF2β.

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Pack Size	Price	Availability
100 μg	$143	35 days
500 μg	$520	35 days
1 mg	$886	35 days

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Product Introduction

Bioactivity

Description

Alias

8-iso-15-keto Prostaglandin F2β

Chemical Properties

Molecular Weight	352.471
Formula	C20H32O5
Cas No.	1621482-36-7

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility Information	Ethanol: 50 mg/mL DMF: 50 mg/mL DMSO: 50 mg/mL PBS (pH 7.2): 1 mg/mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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