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Grosvenorine

Catalog No. TN1714Cas No. 156980-60-8
Alias Grosvenorin

Grosvenorine (Grosvenorin) exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of grosvenorine and significantly affect its pharmacological activities.

Grosvenorine

Grosvenorine

Purity: 99.6%
Catalog No. TN1714Alias GrosvenorinCas No. 156980-60-8
Grosvenorine (Grosvenorin) exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of grosvenorine and significantly affect its pharmacological activities.
Pack SizePriceAvailabilityQuantity
1 mg$88In Stock
5 mg$213In Stock
10 mg$328In Stock
25 mg$552In Stock
50 mg$787In Stock
100 mg$1,070In Stock
1 mL x 10 mM (in DMSO)$272In Stock
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Purity:99.6%
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Product Introduction

Bioactivity
Description
Grosvenorine (Grosvenorin) exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of grosvenorine and significantly affect its pharmacological activities.
In vitro
The Grosvenorine metabolism in an in vitro simulated human gastrointestinal tract (including artificial gastric juice, artificial intestinal juice and intestinal flora), as well as its pharmacological activities (including anti-complement, antibacterial and antioxidant activities), was investigated. The results showed that Grosvenorine was metabolized by human intestinal flora; its four metabolites were isolated by semi-preparative HPLC and identified by NMR as kaempferitrin, afzelin, α±-rhamnoisorobin, and kaempferol. Further pharmacological evaluation showed that Grosvenorine exhibited good antibacterial and antioxidant activities, with its metabolites possessing more potent activities. Although Grosvenorine did not present obvious anticomplement activity, its metabolites showed interesting activities.
AliasGrosvenorin
Chemical Properties
Molecular Weight740.66
FormulaC33H40O19
Cas No.156980-60-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (67.5 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3501 mL6.7507 mL13.5015 mL67.5074 mL
5 mM0.2700 mL1.3501 mL2.7003 mL13.5015 mL
10 mM0.1350 mL0.6751 mL1.3501 mL6.7507 mL
20 mM0.0675 mL0.3375 mL0.6751 mL3.3754 mL
50 mM0.0270 mL0.1350 mL0.2700 mL1.3501 mL

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