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8-​Prenylnaringenin

Catalog No. TN1146Cas No. 53846-50-7
Alias 8-Prenylnaringenin

8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,

8-​Prenylnaringenin

8-​Prenylnaringenin

Purity: 99.46%
Catalog No. TN1146Alias 8-PrenylnaringeninCas No. 53846-50-7
8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,
Pack SizePriceAvailabilityQuantity
1 mg$147In Stock
5 mg$372In Stock
10 mg$548In Stock
25 mg$869In Stock
50 mg$1,170In Stock
100 mg$1,570In Stock
1 mL x 10 mM (in DMSO)$459In Stock
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Purity:99.46%
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Product Introduction

Bioactivity
Description
8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,
In vitro
In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days. 8-PN or TAM were investigated regarding their effect on cell shedding. In vivo, the lower tongue surface of mice was irradiated with graded single doses of 25 kV X-rays. The incidence, latency, and duration of the resulting mucosal ulcerations were analyzed after topical treatment with 8-PN, TAM or solvent. 8-PN or TAM prevented the volume reduction of the irradiated cell aggregates during the incubation period. This was the result of a higher residual cell number in the treated versus the untreated irradiated aggregates. In vivo, topical treatment with 8-PN or TAM significantly increased the latency of mucositis from 10.9 to 12.1 and 12.4 days respectively, while the ulcer incidence was unchanged[1]
Alias8-Prenylnaringenin
Chemical Properties
Molecular Weight340.37
FormulaC20H20O5
Cas No.53846-50-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (66.1 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9380 mL14.6899 mL29.3798 mL146.8990 mL
5 mM0.5876 mL2.9380 mL5.8760 mL29.3798 mL
10 mM0.2938 mL1.4690 mL2.9380 mL14.6899 mL
20 mM0.1469 mL0.7345 mL1.4690 mL7.3449 mL
50 mM0.0588 mL0.2938 mL0.5876 mL2.9380 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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