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Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 in pig lung, trachea, aorta, and pulmonary artery tissue preparations. 15-keto PGA1, given at a concentration of 6 μM, causes vasoconstriction of rabbit lung that is comparable to that induced by angiotensin II.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | Inquiry | 35 days | |
1 mg | Inquiry | 35 days | |
5 mg | Inquiry | 35 days |
Description | Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 in pig lung, trachea, aorta, and pulmonary artery tissue preparations. 15-keto PGA1, given at a concentration of 6 μM, causes vasoconstriction of rabbit lung that is comparable to that induced by angiotensin II. |
Alias | 15-keto Prostaglandin A1 |
Molecular Weight | 334.45 |
Formula | C20H30O4 |
Cas No. | 61600-67-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (149.5 mM), Sonication is recommended. Ethanol: 50 mg/mL (149.5 mM), Sonication is recommended. DMF: 50 mg/mL (149.5 mM), Sonication is recommended. PBS (pH 7.2): 1 mg/mL (2.99 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
PBS (pH 7.2)/DMSO/Ethanol/DMF
DMSO/Ethanol/DMF
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