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BC 11 hydrobromide

🥰Excellent
Catalog No. T22600Cas No. 443776-49-6

BC 11 hydrobromide is a selective TMPRSS2 and urokinase (uPA) inhibitor.BC-11 induces diminished mitochondrial activity, promotes reactive oxygen species production, and promotes apoptosis, and can be used in the study of breast cancer.

BC 11 hydrobromide

BC 11 hydrobromide

🥰Excellent
Purity: 98.07%
Catalog No. T22600Cas No. 443776-49-6
BC 11 hydrobromide is a selective TMPRSS2 and urokinase (uPA) inhibitor.BC-11 induces diminished mitochondrial activity, promotes reactive oxygen species production, and promotes apoptosis, and can be used in the study of breast cancer.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$64In Stock
10 mg$108In Stock
25 mg$239In Stock
50 mg$355In Stock
100 mg$526In Stock
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Purity:98.07%
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Product Introduction

Bioactivity
Description
BC 11 hydrobromide is a selective TMPRSS2 and urokinase (uPA) inhibitor.BC-11 induces diminished mitochondrial activity, promotes reactive oxygen species production, and promotes apoptosis, and can be used in the study of breast cancer.
Targets&IC50
uPA:8.2 μM
Chemical Properties
Molecular Weight290.97
FormulaC8H12BBrN2O2S
Cas No.443776-49-6
SmilesBr.N=C(SCC1=CC=C(C=C1)B(O)O)N
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (343.68 mM), Sonication is recommended.
H2O: 15 mg/mL (51.55 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.4368 mL17.1839 mL34.3678 mL171.8390 mL
5 mM0.6874 mL3.4368 mL6.8736 mL34.3678 mL
10 mM0.3437 mL1.7184 mL3.4368 mL17.1839 mL
20 mM0.1718 mL0.8592 mL1.7184 mL8.5920 mL
50 mM0.0687 mL0.3437 mL0.6874 mL3.4368 mL
DMSO
1mg5mg10mg50mg
100 mM0.0344 mL0.1718 mL0.3437 mL1.7184 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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