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Antiviral agent 35
Antiviral agent 35
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Antiviral agent 35
Catalog No. T79567Cas No. 2760972-52-7
Antiviral agent 35 (compound 4d) serves as a potent orally active inhibitor of the influenza virus, targeting early stages of viral replication. It suppresses influenza-induced ROS accumulation, autophagy, and apoptosis, along with the inflammatory response mediated by the RIG-1 pathway in a mouse model of pulmonary infection. Its cytotoxicity is minimal in MDCK cells, displaying a CC50 greater than 800 μM, and possesses anti-H1N1 (A/Weiss/43) activity with an EC50 of 2.28 μM [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Antiviral agent 35 (compound 4d) serves as a potent orally active inhibitor of the influenza virus, targeting early stages of viral replication. It suppresses influenza-induced ROS accumulation, autophagy, and apoptosis, along with the inflammatory response mediated by the RIG-1 pathway in a mouse model of pulmonary infection. Its cytotoxicity is minimal in MDCK cells, displaying a CC50 greater than 800 μM, and possesses anti-H1N1 (A/Weiss/43) activity with an EC50 of 2.28 μM [1]. |
| In vitro | Antiviral agent 35 (compound 4d), at concentrations of 25 μM and 50 μM over a period of 24 to 72 hours, inhibits the replication of the influenza virus in MDCK cells [1]. |
| In vivo | Antiviral agent 35 (compound 4d), administered to mice orally via gavage at dosages of 25, 50, and 100 mg/kg/day on days 2, 4, and 6 post-H1N1 infection, reduced pulmonary inflammation [1]. |
| Molecular Weight | 418.47 |
| Formula | C23H18N2O4S |
| Cas No. | 2760972-52-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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