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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn's disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus. TargetMol's Anti-Fibrosis Compound Library collects 1800 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product features Product features

  • A unique collection of 1800 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
NF-κB
PI3K
Reactive Oxygen Species
COX
VEGFR
Endogenous Metabolite
PDGFR
MMP
p38 MAPK
Antioxidant
mTOR
Akt
ERK
Wnt/beta-catenin
Antibacterial
TNF
AMPK
Raf
TGF-beta/Smad
GSK-3
c-Kit
CDK
JNK
FGFR
Ras
FLT
MEK
IκB/IKK
Src
IL Receptor
DNA-PK
MAPK
Parasite
EGFR
Antibiotic
CFTR
S6 Kinase
ALK
STAT
Ferroptosis
Caspase
JAK
ATM/ATR
NO Synthase
Mitophagy
HIV Protease
Antifungal
Calcium Channel
Hedgehog/Smoothened
Influenza Virus
Kras
NOD
RIP kinase
Bcr-Abl
Aurora Kinase
PPAR
PKC
Cytochromes P450
PDK
c-Met/HGFR
DNA/RNA Synthesis
ROS
Lipoxygenase
Interleukin
c-RET
Bcl-2 Family
Mitochondrial Metabolism
Nrf2
IRAK
NOD-like Receptor (NLR)
PKA
Rho
PDE
Potassium Channel
NOS
Dehydrogenase
Virus Protease
Tyrosine Kinases
IGF-1R
Casein Kinase
c-Fms
Tyrosinase
ROCK
Topoisomerase
Cholinesterase (ChE)
P-gp
Prostaglandin Receptor
Trk receptor
Beta Amyloid
PI4K
AChR
FAK
HIF/HIF Prolyl-Hydroxylase
MLK
HSV
PGE Synthase
TLR
HDAC
Syk
p53
ATPase
NADPH
Glutathione Peroxidase
TRP/TRPV Channel
Adrenergic Receptor
E1/E2/E3 Enzyme
Smo
Chk
Antiviral
GABA Receptor
Sodium Channel
HER
Chloride channel
HCV Protease
Integrin
Adenosine Receptor
BACE
RAAS
Phosphatase
Serine Protease
SIK
Drug Metabolite
Glucosidase
PTEN
Epigenetic Reader Domain
MNK
SARS-CoV
Proteasome
Carbonic Anhydrase
Transferase
Estrogen/progestogen Receptor
Tie-2
TOPK
Estrogen Receptor/ERR
PARP
CSF-1R
BTK
HSP
Porcupine
Free radical scavengers
Ephrin Receptor
transporter
ASK
Ligand for E3 Ligase
ribosome
LPA Receptor
GPR
Phospholipase
5-HT Receptor
Anti-infection
TAM Receptor
S1P Receptor
Monoamine Oxidase
LPL Receptor
Reductase
c-Myc
MRP
HBV
Serine/threonin kinase
Aryl Hydrocarbon Receptor
IAP
Immunology/Inflammation related
LDL
Molecular Glues
Opioid Receptor
CCR
LRRK2
Retinoid Receptor
KLF
PLK
HIF
SGK
NADPH-oxidase
Mdm2
Proton pump
Histone Methyltransferase
ADC Cytotoxin
LTR
Histamine Receptor
GTPase
Cysteine Protease
Leukotriene Receptor
FXR
RANKL/RANK
MAO
Glucocorticoid Receptor
IRE1
UGT
Gamma-secretase
DNA gyrase
Antifection
DNA Alkylation
ACK1
CaMK
Lipid
Beta-Secretase
Acyltransferase
Aminopeptidase
Sirtuin
PAI-1
MELK
GST
Cannabinoid Receptor
Gap Junction Protein
Microtubule Associated
AhR
PROTACs
Adenylyl Cyclase
GSNOR
NPC1L1
Monocarboxylate transporter
DHFR
ROR
Dynamin
MyD88
YAP
Arginase
IFNAR
DYRK
RAR/RXR 
Histone Demethylase
PERK
gp120/CD4
Galectin
N-Acetylglucosaminyltransferase
AAK1
Hck
Cell Cycle Arrest
Liver X Receptor
PYK2
Amylase
iGluR
Myosin
Haspin Kinase
P2X Receptor
ABC Transporter
Anion Exchanger
Guanylate cyclase
Fatty Acid Synthase
PAK
FAAH
Somatostatin
PAD
cAMP
GluR
DNA
DUB
Indoleamine 2,3-Dioxygenase (IDO)
SGLT
ATP Citrate Lyase
BCRP
OXPHOS
Glutathione reductase
STING
Histone Acetyltransferase
cGAS
Pyroptosis
RSV
Methionine Adenosyltransferase (MAT)
Hippo pathway
GPX
Reverse Transcriptase
Aromatase
CRISPR/Cas9
Hydroxylase
Adenosine Deaminase
Discoidin Domain Receptor (DDR)
Platelet aggregation
BMI-1
cholecystokinin
Thrombin
PD-1/PD-L1
PKM

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