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TargetMol | Compound Library

Anti-Fibrosis Compound Library

Catalog No. L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn’s disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus. TargetMol’s Anti-Fibrosis Compound Library collects 1180 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9810

Anti-Fibrosis Compound Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product features Product features

  • A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
Reactive Oxygen Species
Endogenous Metabolite
COX
VEGFR
Antibacterial
MMP
Antioxidant
NF-κB
TNF
TGF-beta/Smad
FGFR
PDGFR
Wnt/beta-catenin
ROS
IL Receptor
c-Kit
FLT
Antifungal
Parasite
Influenza Virus
ALK
EGFR
Glucocorticoid Receptor
JAK
STAT
Antibiotic
Ferroptosis
NADPH
p38 MAPK
ERK
HIV Protease
Src
P450
NO Synthase
Cannabinoid Receptor
c-Met/HGFR
PPAR
CFTR
Mitophagy
Virus Protease
Nrf2
Caspase
DNA/RNA Synthesis
NOS
Bcr-Abl
Interleukin
AMPK
c-RET
PARP
Calcium Channel
PDE
Lipoxygenase
Akt
PI3K
PKC
BCL
Prostaglandin Receptor
Anti-infection
Tyrosinase
JNK
Tyrosine Kinases
CDK
Mitochondrial Metabolism
Aurora Kinase
Estrogen/progestogen Receptor
Raf
TLR
Trk receptor
GABA Receptor
HIF/HIF Prolyl-Hydroxylase
ROS Kinase
Dehydrogenase
Topoisomerase
SARS-CoV
IκB/IKK
Potassium Channel
TRP/TRPV Channel
Adrenergic Receptor
HSV
Xanthine Oxidase
AChE
P-gp
Beta Amyloid
c-Fms
LPA Receptor
Phospholipase
NADPH-oxidase
NOD-like Receptor (NLR)
HER
ATPase
LPL Receptor
Adenosine Receptor
Glutathione Peroxidase
PKA
Estrogen Receptor/ERR
CSF-1R
Immunology/Inflammation related
CCR
Antiviral
5-HT Receptor
Syk
Sodium Channel
S6 Kinase
TAM Receptor
Chloride channel
Reductase
Histamine Receptor
GSK-3
Cysteine Protease
Drug Metabolite
Chk
Epigenetic Reader Domain
PGE Synthase
MAPK
Free radical scavengers
HDAC
HIF
MEK
AChR
NOD
HCV Protease
RAAS
Phosphatase
Serine Protease
Serine/threonin kinase
Annexin A
UGT
Glucosidase
Molecular Glues
FAAH
mTOR
HSP
Sirtuin
Ephrin Receptor
Casein Kinase
Reverse Transcriptase
Retinoid Receptor
Ligand for E3 Ligase
ribosome
GPR
PDK
Monoamine Oxidase
Proteasome
ROR
Histone Methyltransferase
Integrin
LTR
BACE
Lipase
Tie-2
MRP
HBV
Leukotriene Receptor
MAO
IAP
IRE1
RIP kinase
Gamma-secretase
P2X Receptor
DNA gyrase
Antifection
Opioid Receptor
Smo
Hedgehog/Smoothened
CXCR
PTEN
Epoxide Hydrolase
IGF-1R
Indoleamine 2,3-Dioxygenase (IDO)
Porcupine
Aminopeptidase
Histone Acetyltransferase
PAI-1
RSV
Aromatase
Gap Junction Protein
Discoidin Domain Receptor (DDR)
Microtubule Associated
FAK
MLK
p53
advanced glycation end products
Proton pump
Carbonic Anhydrase
Transferase
Monocarboxylate transporter
Hydrogenase
Dynamin
MyD88
Amino Acids and Derivatives
IFNAR
RAR/RXR 
Progesterone Receptor
Melatonin Receptor
Galectin
c-Myc
CaSR
N-Acetylglucosaminyltransferase
Rho
Hck
cell cycle arrest
Liver X Receptor
RANKL/RANK
ROCK
Amylase
iGluR
FLAP
E1/E2/E3 Enzyme
Adiponectin receptor
LDL
AAK1 (AP2 associated kinase 1)
Phosphorylase
BTK
Anion Exchanger
Guanylate cyclase
PAK
Somatostatin
PAD
CaMK
DNA
Androgen Receptor
Telomerase
SGLT
ATP Citrate Lyase
OXPHOS
Glutathione reductase
Survivin
transporter
ASK
hCE
Pyroptosis
ATM/ATR
GST
Hydroxylase
PLK
Platelet aggregation
DNA Methyltransferase
IRAK
Ras
HMG-CoA Reductase
Thrombin
PKM

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