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Anti-Fibrosis Compound Library

Catalog No. L9810
  Library Compound List   Excel SDF

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn’s disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol’s Anti-Fibrosis Compound Library collects 1180 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product features

  • A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS;
  • Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
  • Some compounds are in the market (FDA-approved);
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L9810)

Library Composition

VEGFR (94)
COX (91)
Antioxidant (79)
TNF (61)
PDGFR (53)
FGFR (50)
NF-κB (48)
MMP (43)
Wnt/beta-catenin (39)
ROS (39)
IL Receptor (34)
c-Kit (30)
TGF-beta/Smad (30)
Glucocorticoid Receptor (28)
EGFR (24)
FLT (22)
ALK (22)
STAT (20)
Src (20)
JAK (19)
PPAR (18)
Cannabinoid Receptor (18)
Autophagy (17)
NADPH (17)
Apoptosis (16)
Antibacterial (16)
P450 (16)
p38 MAPK (14)
ERK (14)
CFTR (14)
c-Met/HGFR (14)
NOS (13)
Antifection (13)
Endogenous Metabolite (13)
Bcr-Abl (12)
Caspase (11)
PKC (10)
c-RET (10)
PDE (10)
Tyrosine Kinases (9)
Tyrosinase (9)
DNA/RNA Synthesis (9)
Akt (9)
BCL (9)
Lipoxygenase (8)
Prostaglandin Receptor (8)
Estrogen/progestogen Receptor (8)
AChR (8)
HIV Protease (8)
CDK (8)
Antifungal (7)
Raf (7)
AMPK (7)
GABA Receptor (7)
Adrenergic Receptor (7)
Aurora Kinase (7)
IκB/IKK (7)
NADPH-oxidase (6)
LPA Receptor (6)
JNK (6)
PI3K (6)
HER (6)
Antiviral (6)
Phospholipase (6)
Potassium Channel (6)
Vitamin (6)
Trk receptor (6)
Dehydrogenase (5)
CSF-1R (5)
HIF (5)
PKA (5)
TLR (5)
ATPase (5)
Antibiotic (5)
Histamine Receptor (4)
HSP (4)
TAM Receptor (4)
Nrf2 (4)
Syk (4)
S6 Kinase (4)
NOD (4)
Mitochondrial Metabolism (4)
Reductase (4)
Reactive Oxygen Species (4)
PARP (4)
MAPK (4)
5-HT Receptor (4)
Immunology & Inflammation related (4)
Chk (4)
Free radical scavengers (4)
GSK-3 (4)
Epigenetic Reader Domain (4)
Cysteine Protease (4)
CCR (4)
c-Fms (3)
PDK (3)
Serine Protease (3)
Glucokinase (3)
Sirtuin (3)
ribosome (3)
NO Synthase (3)
Beta Amyloid (3)
mTOR (3)
Retinoid Receptor (3)
MRP (3)
MPO (3)
RAAS (3)
MEK (3)
Annexin A (3)
Topoisomerase (3)
TRP/TRPV Channel (3)
UGT (3)
Calcium Channel (3)
Androgen Receptor (2)
BACE (2)
p53 (2)
IAP (2)
Parasite (2)
CXCR (2)
Hedgehog/Smoothened (2)
Chloride channel (2)
LTR (2)
DNA gyrase (2)
Hck (2)
Casein Kinase (2)
Carbonic Anhydrase (2)
Proteasome (2)
HDAC (2)
Adenosine Receptor (2)
LDL (2)
MAO (2)
Ephrin Receptor (2)
Aromatase (2)
Tie-2 (2)
Microtubule Associated (2)
MLK (2)
Glutathione reductase (2)
GPR (2)
Integrin (2)
Influenza Virus (2)
IGF-1R (2)
Survivin (1)
Anion Exchanger (1)
ATM/ATR (1)
Somatostatin (1)
Thrombin (1)
Reverse Transcriptase (1)
Sodium Channel (1)
Transferase (1)
Adiponectin receptor (1)
ROCK (1)
ROR (1)
Serine/threonin kinase (1)
Telomerase (1)
advanced glycation end products (1)
Aminopeptidase (1)
ATP Citrate Lyase (1)
Amino Acids and Derivatives (1)
AhR (1)
SGLT (1)
transporter (1)
ASK (1)
SARS-CoV (1)
HIF/HIF Prolyl-Hydroxylase (1)
BTK (1)
Keap1-Nrf (1)
Monoamine Oxidase (1)
Gamma-secretase (1)
Melatonin Receptor (1)
Gap Junction Protein (1)
GHSR (1)
Lipase (1)
GST (1)
N-Acetylglucosaminyltransferase (1)
Guanylate cyclase (1)
IDO (1)
Hydroxylase (1)
Hydrogenase (1)
HSV (1)
HMG-CoA Reductase (1)
Histone Methyltransferase (1)
Monocarboxylate transporter (1)
FLAP (1)
RAR/RXR (1)
PGE Synthase (1)
PTEN (1)
CaMK (1)
PLK (1)
PKM (1)
cell cycle arrest (1)
Phosphatase (1)
P-gp (1)
PAI-1 (1)
Ferroptosis (1)
PAFR (1)
Discoidin Domain Receptor (DDR) (1)
P2 Receptor (1)
OXPHOS (1)
DNA Alkylation (1)
Opioid Receptor (1)
FAAH (1)
c-Myc (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE