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Prostaglandin I3 (sodium salt)

Name: Prostaglandin I3 (sodium salt)
Brand: TargetMol
SKU: T36546
Rating: 4.5 (1 reviews)

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Catalog No. T36546Cas No. 68324-96-9

Alias Prostaglandin I3 (sodium salt)

PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.

Prostaglandin I3 (sodium salt)

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Catalog No. T36546Alias Prostaglandin I3 (sodium salt)Cas No. 68324-96-9

Pack Size	Price	Availability
50 μg	Inquiry	35 days
100 μg	Inquiry	35 days
500 μg	Inquiry	35 days
1 mg	Inquiry	35 days

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Product Introduction

Bioactivity

Description	PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.
Alias	Prostaglandin I3 (sodium salt)

Chemical Properties

Molecular Weight	372.43
Formula	C₂₀H₂₉NaO₅
Cas No.	68324-96-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

PBS (pH >10.2): 10 mg/mL (26.85 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH >10.2)

	1mg	5mg	10mg	50mg
1 mM	2.6851 mL	13.4253 mL	26.8507 mL	134.2534 mL
5 mM	0.5370 mL	2.6851 mL	5.3701 mL	26.8507 mL
10 mM	0.2685 mL	1.3425 mL	2.6851 mL	13.4253 mL
20 mM	0.1343 mL	0.6713 mL	1.3425 mL	6.7127 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Prostaglandin I-3 (sodium salt)Prostaglandin I3

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