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Sonlicromanol hydrochloride
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Sonlicromanol hydrochloride
Catalog No. T38013Cas No. 2162149-24-6
Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator that crosses the blood-brain barrier, has potential anticancer activity, improves m.3243A>G heterogeneity in iPSC-derived neurons associated with It has potential anticancer activity, ameliorates neuronal network dysfunction and transcriptomic changes associated with m.3243A>G heterogeneity in iPSC-derived neurons, and can be used for the treatment of mitochondrial diseases.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $158 | In Stock | |
| 5 mg | $396 | In Stock | |
| 10 mg | $662 | In Stock | |
| 25 mg | $1,360 | In Stock | |
| 50 mg | $1,980 | In Stock | |
| 100 mg | $2,500 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator that crosses the blood-brain barrier, has potential anticancer activity, improves m.3243A>G heterogeneity in iPSC-derived neurons associated with It has potential anticancer activity, ameliorates neuronal network dysfunction and transcriptomic changes associated with m.3243A>G heterogeneity in iPSC-derived neurons, and can be used for the treatment of mitochondrial diseases. |
| In vivo | In Ndufs4−/− mice (Leigh Disease model), Sonlicromanol hydrochloride (10 mg/kg; intraperitoneal injection, once daily) significantly improved rotarod and gait performance, reduced degeneration of retinal ganglion cells. Additionally, it resulted in significantly higher FA values in the external capsule and showed a similar trend in the cerebral peduncle[1]. |
| Alias | KH 176 hydrochloride |
| Molecular Weight | 368.9 |
| Formula | C19H29ClN2O3 |
| Cas No. | 2162149-24-6 |
| Storage | store under nitrogen,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 150 mg/mL (406.61 mM) H2O: 80 mg/mL (216.86 mM.) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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