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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,140 | 6-8 weeks | |
50 mg | $2,785 | 6-8 weeks | |
100 mg | $3,520 | 6-8 weeks |
Description | Anti-osteoporosis agent-1 (comp 4aa) is a potent RPA (replication protein A) inhibitor with an IC50 value of 18 μM [1]. |
In vitro | Anti-osteoporosis agent-1 effectively promotes osteoblast mineralization and enhances the expression of osteogenic marker genes, including Bmp-2, Runx-2, and Type-1col, at both transcriptional and translational levels. It demonstrates significant osteogenic activity and notable anti-apoptotic properties at 1 pM and 100 pM, increasing osteoblast survival under serum-deprived conditions [1]. |
Molecular Weight | 354.83 |
Formula | C20H19ClN2O2 |
Cas No. | 2761577-50-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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