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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $125 | In Stock | |
5 mg | $313 | In Stock | |
10 mg | $497 | In Stock | |
25 mg | $793 | In Stock | |
50 mg | $1,130 | In Stock | |
100 mg | $1,520 | In Stock | |
500 mg | $2,970 | In Stock | |
1 mL x 10 mM (in DMSO) | $345 | In Stock |
Description | v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency. Rosabulin inhibits microtubule assembly and has broad-spectrum antitumor activity. |
In vitro | Rosabulin is inhibition of microtubule assembly and subsequent arrest of the cell cycle. Rosabulin is active against several tumor cell lines that express moderate to high levels of P-glycoprotein. Rosabulin shows substantial anti-proliferative activity against a wide range of cancer cell lines in vitro, with IC50 values extending down into the nanomolar range.[1] |
In vivo | Rosabulin has displayed in vivo activity in several murine tumors as well as human tumor xenograft models.[1] |
Alias | STA 5312 |
Molecular Weight | 400.45 |
Formula | C22H16N4O2S |
Cas No. | 501948-05-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 25 mg/mL (62.43 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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