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Albendazole

Catalog No. T1152Cas No. 54965-21-8
Alias SKF-62979

Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.

Albendazole

Albendazole

Purity: 98.76%
Catalog No. T1152Alias SKF-62979Cas No. 54965-21-8
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
Pack SizePriceAvailabilityQuantity
50 mg$40In Stock
100 mg$48In Stock
200 mg$59In Stock
500 mg$81In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:98.76%
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Product Introduction

Bioactivity
Description
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
In vitro
In sheep lambs administered Albendazole intravenously, the drug and its active metabolite, albendazole sulfoxide, are recovered in tapeworms. In rats, Albendazole significantly increases hepatic activity: it induces a 65-fold increase in CYP1A1-related ethoxyresorufin O-deethylase (EROD) activity, a 6-fold increase in CYP1A2-related methoxyresorufin O-demethylase activity, a 4-fold increase in CYP2B1-related pentoxyresorufin O-dealkylase activity, a 14-fold increase in CYP2B2-related benzyloxyresorufin O-dealkylase activity, and also leads to a partial reduction in CYP2E1-related p-nitrophenol hydroxylase activity. Albendazole is metabolized by liver and lung microsomes in sheep and cattle as well as bovine intestinal microsomes into its pharmacologically active sulfoxide metabolite.
In vivo
Albendazole and its sulfoxide metabolites induce the accumulation of cells in the mitotic phase.
AliasSKF-62979
Chemical Properties
Molecular Weight265.33
FormulaC12H15N3O2S
Cas No.54965-21-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (37.69 mM), Sonication is recommended.
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7689 mL18.8445 mL37.6889 mL188.4446 mL
5 mM0.7538 mL3.7689 mL7.5378 mL37.6889 mL
10 mM0.3769 mL1.8844 mL3.7689 mL18.8445 mL
20 mM0.1884 mL0.9422 mL1.8844 mL9.4222 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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