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Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $40 | In Stock | |
100 mg | $48 | In Stock | |
200 mg | $59 | In Stock | |
500 mg | $81 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations. |
In vitro | In sheep lambs administered Albendazole intravenously, the drug and its active metabolite, albendazole sulfoxide, are recovered in tapeworms. In rats, Albendazole significantly increases hepatic activity: it induces a 65-fold increase in CYP1A1-related ethoxyresorufin O-deethylase (EROD) activity, a 6-fold increase in CYP1A2-related methoxyresorufin O-demethylase activity, a 4-fold increase in CYP2B1-related pentoxyresorufin O-dealkylase activity, a 14-fold increase in CYP2B2-related benzyloxyresorufin O-dealkylase activity, and also leads to a partial reduction in CYP2E1-related p-nitrophenol hydroxylase activity. Albendazole is metabolized by liver and lung microsomes in sheep and cattle as well as bovine intestinal microsomes into its pharmacologically active sulfoxide metabolite. |
In vivo | Albendazole and its sulfoxide metabolites induce the accumulation of cells in the mitotic phase. |
Alias | SKF-62979 |
Molecular Weight | 265.33 |
Formula | C12H15N3O2S |
Cas No. | 54965-21-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 10 mg/mL (37.69 mM), Sonication is recommended. H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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