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11β-Hydroxyandrosterone

Name: 11β-Hydroxyandrosterone
Brand: TargetMol
SKU: T73780
Price: 29 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T73780Cas No. 57-61-4

11β-Hydroxyandrosterone is a urinary adrenal-derived androgen metabolite in children with CAH.

11β-Hydroxyandrosterone

😃Good

Catalog No. T73780Cas No. 57-61-4

11β-Hydroxyandrosterone is a urinary adrenal-derived androgen metabolite in children with CAH.

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50 mg	Inquiry	Backorder

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COA

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	11β-Hydroxyandrosterone is a urinary adrenal-derived androgen metabolite in children with CAH.
In vitro	Among the metabolites of DHEA, AD4, and 11OHAD4, only 11β-Hydroxyandrosterone (a metabolite of 11OHAD4) showed no overlap between C21OHD (classic 21-hydroxylase deficiency) and PORD (cytochrome P450 oxidoreductase deficiency) at a threshold of 0.35 mg/g creatinine. Detection of 11β-Hydroxyandrosterone distinguished the two. [1]

Chemical Properties

Molecular Weight	306.44
Formula	C₁₉H₃₀O₃
Cas No.	57-61-4
Smiles	C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)C(=O)CC4)[H])(CC[C@]1(C[C@H](O)CC2)[H])[H])[H]

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (261.06 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2633 mL	16.3164 mL	32.6328 mL	163.1641 mL
5 mM	0.6527 mL	3.2633 mL	6.5266 mL	32.6328 mL
10 mM	0.3263 mL	1.6316 mL	3.2633 mL	16.3164 mL
20 mM	0.1632 mL	0.8158 mL	1.6316 mL	8.1582 mL
50 mM	0.0653 mL	0.3263 mL	0.6527 mL	3.2633 mL
100 mM	0.0326 mL	0.1632 mL	0.3263 mL	1.6316 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc