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Urolithin C
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
Catalog No. TN7108Cas No. 165393-06-6
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Purity:98.16%
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Urolithin C
Catalog No. TN7108Cas No. 165393-06-6
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $48 | In Stock | |
| 10 mg | $80 | In Stock | |
| 25 mg | $146 | In Stock | |
| 50 mg | $247 | In Stock | |
| 100 mg | $372 | In Stock | |
| 200 mg | $549 | In Stock | |
| 500 mg | $869 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $54 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway. |
| In vitro | Urolithin C is a glucose-dependent activator of insulin secretion acting by facilitating L-type Ca2+ channel opening and Ca2+ influx into pancreatic β-cells.Urolithin C enhanced glucose-induced extracellular signal-regulated kinases 1/2 (ERK1/2) activation as shown by higher phosphorylation levels in INS-1 β-cells[2]. Urolithin C stimulates reactive oxygen species (ROS) formation[2]. |
| In vivo | In male Wistar rat, the half-life of the terminal part is 11.3 h and the total clearance (CL/F) is 3.41 L/h/kg. The initial volume of distribution (V1/F) is 0.831 L/kg and the steady-state volume of distribution (Vss/F) is 55.6 L/kg after the intraperitoneal administration of Urolithin C (10 mg/kg)[3]. |
| Molecular Weight | 244.2 |
| Formula | C13H8O5 |
| Cas No. | 165393-06-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (204.75 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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