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20-hydroxy Prostaglandin F2α

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Catalog No. T37840Cas No. 57930-92-4
Alias 20-hydroxy Prostaglandin F2α

20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites [20-hydroxy PGF2α and 15-hydroxy PGDH]. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.

20-hydroxy Prostaglandin F2α

20-hydroxy Prostaglandin F2α

😃Good
Catalog No. T37840Alias 20-hydroxy Prostaglandin F2αCas No. 57930-92-4
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites [20-hydroxy PGF2α and 15-hydroxy PGDH]. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.
Pack SizePriceAvailabilityQuantity
50 μg$36035 days
100 μg$68635 days
500 μg$1,24035 days
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Product Introduction

Bioactivity
Description
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites [20-hydroxy PGF2α and 15-hydroxy PGDH]. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.
Alias20-hydroxy Prostaglandin F2α
Chemical Properties
Molecular Weight370.486
FormulaC20H34O6
Cas No.57930-92-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
10 mM Na2CO3: >6.5 mg/mL (from PGF2a)
Ethanol: >100 mg/mL (from PGF2a)
DMF: >100 mg/mL (from PGF2a)
PBS (pH 7.2): >10 mg/mL (from PGF2a)
DMSO: >100 mg/mL (from PGF2a)

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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