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20-hydroxy Prostaglandin F2α

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20-hydroxy Prostaglandin F2α

Catalog No. T37840Cas No. 57930-92-4

20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites [20-hydroxy PGF2α and 15-hydroxy PGDH]. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.

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Pack Size	Price	Availability
50 μg	$160	35 days
100 μg	$686	35 days
500 μg	$1,240	35 days

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Product Introduction

Bioactivity

Description	20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites [20-hydroxy PGF2α and 15-hydroxy PGDH]. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.
Alias	20-hydroxy Prostaglandin F2α

Chemical Properties

Molecular Weight	370.486
Formula	C20H34O6
Cas No.	57930-92-4

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility Information	10 mM Na2CO3: >6.5 mg/mL (from PGF2a) Ethanol: >100 mg/mL (from PGF2a) DMF: >100 mg/mL (from PGF2a) PBS (pH 7.2): >10 mg/mL (from PGF2a) DMSO: >100 mg/mL (from PGF2a)

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

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Keywords

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