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Tyrosine kinase inhibitor
🥰Excellent
Catalog No. T17184Cas No. 1021950-26-4
Tyrosine kinase inhibitor is a tyrosine kinase inhibitor used in combination with fragmenting aromatic nitrogen compounds as antiproliferative agents.
Tyrosine kinase inhibitor
🥰Excellent
Catalog No. T17184Cas No. 1021950-26-4
Tyrosine kinase inhibitor is a tyrosine kinase inhibitor used in combination with fragmenting aromatic nitrogen compounds as antiproliferative agents.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Tyrosine kinase inhibitor is a tyrosine kinase inhibitor used in combination with fragmenting aromatic nitrogen compounds as antiproliferative agents. |
| In vitro | Tyrosine kinases play crucial roles in diverse biological processes such as growth, differentiation, metabolism, and apoptosis in response to stimuli. Recent findings highlight their involvement in cancer pathophysiology. Although normally regulated, tyrosine kinases may gain transforming functions through mutation(s), overexpression, or autocrine/paracrine stimulation, causing malignancy. Selective tyrosine kinase inhibitors can block constitutive oncogenic activation in cancer cells, offering a promising approach for innovative genome-based therapeutics. |
| Molecular Weight | 586.61 |
| Formula | C31H31FN6O5 |
| Cas No. | 1021950-26-4 |
| Smiles | Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc4[nH]c(cc34)C(=O)NCCN3CCOCC3)cc2)cc1 |
| Relative Density. | 1.428 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (76.71 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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