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Isoborneol

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Catalog No. T7983Cas No. 124-76-5
Alias DL-Isoborneol

Isoborneol (DL-Isoborneol) is a monoterpene alcohol, with neuroprotective and antiviral activities

Isoborneol

Isoborneol

🥰Excellent
Catalog No. T7983Alias DL-IsoborneolCas No. 124-76-5
Isoborneol (DL-Isoborneol) is a monoterpene alcohol, with neuroprotective and antiviral activities
Pack SizePriceAvailabilityQuantity
500 mg37 €In Stock
1 mL x 10 mM (in DMSO)27 €In Stock
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Product Introduction

Bioactivity
Description
Isoborneol (DL-Isoborneol) is a monoterpene alcohol, with neuroprotective and antiviral activities
In vitro
Isoborneol, a monoterpene and a component of several plant essential oils, showed dual viricidal activity against herpes simplex virus 1 (HSV-1).?First, it inactivated HSV-1 by almost 4 log10 values within 30 min of exposure, and second, isoborneol at a concentration of 0.06% completely inhibited viral replication, without affecting viral adsorption.?Isoborneol did not exhibit significant cytotoxicity at concentrations ranging between 0.016% and 0.08% when tested against human and monkey cell lines.?Isoborneol specifically inhibited glycosylation of viral polypeptides based on the following data:?(1) the mature fully glycosylated forms of two viral glycoproteins gB and gD were not detected when the virus was replicated in the presence of isoborneol, (2) no major changes were observed in the glycosylation pattern of cellular polypeptides between untreated and isoborneol treated Vero cells, (3) isoborneol did not affect the glycosylation of gB produced from a copy of the gB gene resident in the cellular genome, and (4) other monoterpenes such as 1,8-cineole and borneol,?a stereoisomer of isoborneol, did not inhibit HSV-1 glycosylation[1].
AliasDL-Isoborneol
Chemical Properties
Molecular Weight154.25
FormulaC10H18O
Cas No.124-76-5
SmilesCC1(C)[C@@H]2CC[C@@]1(C)[C@H](O)C2
Relative Density.0.992g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 9 mg/mL (58.35 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.4830 mL32.4149 mL64.8298 mL324.1491 mL
5 mM1.2966 mL6.4830 mL12.9660 mL64.8298 mL
10 mM0.6483 mL3.2415 mL6.4830 mL32.4149 mL
20 mM0.3241 mL1.6207 mL3.2415 mL16.2075 mL
50 mM0.1297 mL0.6483 mL1.2966 mL6.4830 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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