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Rosiglitazone maleate

Rosiglitazone maleate
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Purity:99.33%
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Rosiglitazone maleate

Catalog No. T1622Cas No. 155141-29-0
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.
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Pack SizePriceAvailabilityQuantity
25 mg$36In Stock
50 mg$52In Stock
100 mg$84In Stock
200 mg$150In Stock
500 mg$249In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Related Compound Libraries of "Rosiglitazone maleate"

Product Introduction

Bioactivity
Description
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.
In vivo
In numerous cell lines, Rosiglitazone has been found to inhibit cholesterol synthesis. It activates the AMP-activated protein kinase (AMPK) complex, which includes the α1 and α2 subunits within the AMPKα subunit, leading to an increase in phosphorylation.
AliasBRL 49653C, BRL 49653
Chemical Properties
Molecular Weight473.5
FormulaC22H23N3O7S
Cas No.155141-29-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 87 mg/mL (183.9 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1119 mL10.5597 mL21.1193 mL105.5966 mL
5 mM0.4224 mL2.1119 mL4.2239 mL21.1193 mL
10 mM0.2112 mL1.0560 mL2.1119 mL10.5597 mL
20 mM0.1056 mL0.5280 mL1.0560 mL5.2798 mL
50 mM0.0422 mL0.2112 mL0.4224 mL2.1119 mL
100 mM0.0211 mL0.1056 mL0.2112 mL1.0560 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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