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Rosiglitazone maleate
Catalog No. T1622Cas No. 155141-29-0
Alias BRL 49653C, BRL 49653
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.
Rosiglitazone maleate
Catalog No. T1622Alias BRL 49653C, BRL 49653Cas No. 155141-29-0
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $29 | In Stock | |
| 100 mg | $48 | In Stock | |
| 500 mg | $147 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock |
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Purity:99.76%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. |
| Targets&IC50 | PPARγ:42 nM |
| In vivo | In numerous cell lines, Rosiglitazone has been found to inhibit cholesterol synthesis. It activates the AMP-activated protein kinase (AMPK) complex, which includes the α1 and α2 subunits within the AMPKα subunit, leading to an increase in phosphorylation. |
| Alias | BRL 49653C, BRL 49653 |
| Molecular Weight | 473.5 |
| Formula | C22H23N3O7S |
| Cas No. | 155141-29-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: < 1 mg/mL (insoluble or slightly soluble) DMSO: 87 mg/mL (183.9 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||||||||||||
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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